ArticleBMC genetics2018
Characterization of the late embryogenesis abundant (LEA) proteins family and their role in drought stress tolerance in upland cotton.
Article in BMC genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 123 papers.
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123 citing papers in PubMed, 296 citations in OpenAlex.
- Characterization, evolution, and expression profiling of cotton DUF677 protein family and their potential role in drought and salt stress response.BMC plant biology · 2026Article
- GmPP2C113, a Soybean Protein Phosphatase, Positively Regulates Both Salt Tolerance and Symbiotic Nodulation.Genes · 2026Article
- Overexpression of the tomato SlLEA_2-26 gene enhances the tolerance to drought and salt stresses in Arabidopsis thaliana.Journal of plant research · 2026Article
- Genome-wide identification, evolution, and expression pattern analysis of the LEA gene family in Tartary Buckwheat (Fagopyrum tataricum).BMC genomics · 2026Article
- Divergent Transcriptional Architectures Beyond Core CAM Genes in Facultative and Constitutive CAM Species in Tillandsia L.Molecular ecology · 2026Article
- The Arabidopsis Mutant of the Small Intrinsically Disordered Protein DSS1(V) Exhibits Increased Sensitivity to Drought Stress.Plant direct · 2026Article
- Molecular networks and signaling pathways governing abiotic stress tolerance in cotton: advances and perspectives.Functional & integrative genomics · 2026Review
- Comparative efficacy of gibberellic acid and melatonin seed priming on germination and biochemical responses of maize under drought stress.Frontiers in plant science · 2026Article
- Review
- Mapping novel yellow and leaf rust loci and predicting resistance in cross derived Canadian durum wheat.The plant genome · 2025Article
- Genome-wide identification, structural characterization and gene expression analysis of the LEA_2 gene family in faba bean (Vicia Faba L.).BMC plant biology · 2025Article
- Genome-Wide Analysis of theBiology · 2025Article
- Surviving desiccation: key factors underlying tolerance in prokaryotes and eukaryotes.Protoplasma · 2025Review
- Duckweed Evolution: from Land back to Water.Genomics, proteomics & bioinformatics · 2025Article
- Plant-fungus synergy against soil salinity: The cellular and molecular role of arbuscular mycorrhizal fungi.iScience · 2025Review
- Whole genome duplication drives transcriptome reprogramming in response to drought in alfalfa.Plant cell reports · 2025Article
- Genome-wide identification and characterization of DUF789 genes in cotton: implications for fibre development.BMC plant biology · 2025Article
- Genome-Wide Dissection of MATE Gene Family in Cultivated Peanuts and Unveiling Their Expression Profiles Under Aluminum Stress.International journal of molecular sciences · 2025Article
- Article
- Genome-Wide Association and Genomic Prediction of Alfalfa (International journal of molecular sciences · 2025Article
63 more citing papers are in PubMed but not listed here.
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Authors and funding
11 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLate embryogenesis abundant (LEA) proteins are large groups of hydrophilic proteins with major role in drought and other abiotic stresses tolerance in plants. In-depth study and characterization of LEA protein families have been carried out in other plants, but not in upland cotton. The main aim of this research work was to characterize the late embryogenesis abundant (LEA) protein families and to carry out gene expression analysis to determine their potential role in drought stress tolerance in upland cotton. Increased cotton production in the face of declining precipitation and availability of fresh water for agriculture use is the focus for breeders, cotton being the backbone of textile industries and a cash crop for many countries globally.
resultsIn this work, a total of 242, 136 and 142 LEA genes were identified in G. hirsutum, G. arboreum and G. raimondii respectively. The identified genes were classified into eight groups based on their conserved domain and phylogenetic tree analysis. LEA 2 were the most abundant, this could be attributed to their hydrophobic character. Upland cotton LEA genes have fewer introns and are distributed in all chromosomes. Majority of the duplicated LEA genes were segmental. Syntenic analysis showed that greater percentages of LEA genes are conserved. Segmental gene duplication played a key role in the expansion of LEA genes. Sixty three miRNAs were found to target 89 genes, such as miR164, ghr-miR394 among others. Gene ontology analysis revealed that LEA genes are involved in desiccation and defense responses. Almost all the LEA genes in their promoters contained ABRE, MBS, W-Box and TAC-elements, functionally known to be involved in drought stress and other stress responses. Majority of the LEA genes were involved in secretory pathways. Expression profile analysis indicated that most of the LEA genes were highly expressed in drought tolerant cultivars Gossypium tomentosum as opposed to drought susceptible, G. hirsutum. The tolerant genotypes have a greater ability to modulate genes under drought stress than the more susceptible upland cotton cultivars.
conclusionThe finding provides comprehensive information on LEA genes in upland cotton, G. hirsutum and possible function in plants under drought stress.
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