Evidence map›Paper›PMID 29334888›Full record

ArticleBMC bioinformatics2018

diceR: an R package for class discovery using an ensemble driven approach.

Derek S Chiu, Aline Talhouk

Abstract read
In one paragraph

Article in BMC bioinformatics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Ensemble clustering: A practical tutorial.Behavior research methods · 2026
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  11. Patterns in GP appointment systems: a cluster analysis of 3480 English practices.The British journal of general practice : the journal of the Royal College of General Practitioners · 2025
    Article
  12. Trophic convergence of marine vertebrate communities worldwide.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
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  18. The Prognostic Effect of Immune Cell Infiltration Depends on Molecular Subtype in Endometrioid Ovarian Carcinomas.Clinical cancer research : an official journal of the American Association for Cancer Research · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Derek S ChiuDepartment of Molecular Oncology, BC Cancer Agency, Vancouver, BC, Canada.
Aline TalhoukDepartment of Molecular Oncology, BC Cancer Agency, Vancouver, BC, Canada. atalhouk@bccrc.ca.ORCID 0000-0001-7760-410X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGiven a set of features, researchers are often interested in partitioning objects into homogeneous clusters. In health research, cancer research in particular, high-throughput data is collected with the aim of segmenting patients into sub-populations to aid in disease diagnosis, prognosis or response to therapy. Cluster analysis, a class of unsupervised learning techniques, is often used for class discovery. Cluster analysis suffers from some limitations, including the need to select up-front the algorithm to be used as well as the number of clusters to generate, in addition, there may exist several groupings consistent with the data, making it very difficult to validate a final solution. Ensemble clustering is a technique used to mitigate these limitations and facilitate the generalization and reproducibility of findings in new cohorts of patients.

resultsWe introduce diceR (diverse cluster ensemble in R), a software package available on CRAN: https://CRAN.R-project.org/package=diceR

conclusionsdiceR is designed to provide a set of tools to guide researchers through a general cluster analysis process that relies on minimizing subjective decision-making. Although developed in a biological context, the tools in diceR are data-agnostic and thus can be applied in different contexts.

Indexed as

AlgorithmsSoftwareCluster AnalysisDatabases as TopicHumansCancerCluster analysisConsensusData miningEnsemble

Identifiers

PMID29334888
PMCPMC5769335

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.