ArticleJournal of neurotrauma2018
The Influence of Traumatic Axonal Injury in Thalamus and Brainstem on Level of Consciousness at Scene or Admission: A Clinical Magnetic Resonance Imaging Study.
Article in Journal of neurotrauma, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group.Brain imaging and behavior · 2021Pooled it
- Regional brain volume prior to treatment is linked to outcome after cognitive rehabilitation in traumatic brain injury.NeuroImage. Clinical · 2022Trial
- Differences in the Subcortical White Matter Integrity Based on the Disorder of Consciousness at the Chronic Stage of Diffuse Axonal Injury: A Tract-Based Spatial Statistics Study.Medicina (Kaunas, Lithuania) · 2026Article
- Prognostic Value of Early Magnetic Resonance Imaging Lesion Topography in Diffuse Axonal Injury: The KASHI Classification: An Institute-Based Experience.Asian journal of neurosurgery · 2026Article
- Water channel changes in astrocytes associated with buprenorphine administration in a rat model of diffuse traumatic brain injury.Research square · 2026Article
- Moderate and severe traumatic brain injury: abbreviated injury scale scoring and coding of traumatic axonal injury from early MRI.BMC emergency medicine · 2025Article
- Significance of the corpus callosum and inferior fronto-occipital fasciculus in recovery after traumatic brain injury.Neuroradiology · 2025Article
- Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice.Nature communications · 2025Article
- Improvement in Functional Outcome from 6 to 12 Months After Moderate and Severe Traumatic Brain Injury Is Frequent, But May Not Be Detected With the Glasgow Outcome Scale Extended.Neurotrauma reports · 2024Article
- The biomechanical signature of loss of consciousness: computational modelling of elite athlete head injuries.Brain : a journal of neurology · 2023Review
- Extended Analysis of Axonal Injuries Detected Using Magnetic Resonance Imaging in Critically Ill Traumatic Brain Injury Patients.Journal of neurotrauma · 2022Article
- Patients with Mild Traumatic Brain Injury Recruited from Both Hospital and Primary Care Settings: A Controlled Longitudinal Magnetic Resonance Imaging Study.Journal of neurotrauma · 2019Article
- Investigation on the Neural Mechanism of Hypnosis-Based Respiratory Control Using Functional MRI.Contrast media & molecular imaging · 2018Article
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Authors and funding
7 authors.
Funding
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Abstract
The aim of this study was to investigate how traumatic axonal injury (TAI) lesions in the thalamus, basal ganglia, and brainstem on clinical brain magnetic resonance imaging (MRI) are associated with level of consciousness in the acute phase in patients with moderate to severe traumatic brain injury (TBI). There were 158 patients with moderate to severe TBI (7-70 years) with early 1.5T MRI (median 7 days, range 0-35) without mass lesion included prospectively. Glasgow Coma Scale (GCS) scores were registered before intubation or at admission. The TAI lesions were identified in T2*gradient echo, fluid attenuated inversion recovery, and diffusion weighted imaging scans. In addition to registering TAI lesions in hemispheric white matter and the corpus callosum, TAI lesions in the thalamus, basal ganglia, and brainstem were classified as uni- or bilateral. Twenty percent of patients had TAI lesions in the thalamus (7% bilateral), 18% in basal ganglia (2% bilateral), and 29% in the brainstem (9% bilateral). One of 26 bilateral lesions in the thalamus or brainstem was found on computed tomography. The GCS scores were lower in patients with bilateral lesions in the thalamus (median four) and brainstem (median five) than in those with corresponding unilateral lesions (median six and eight,
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