Trial reportJournal of diabetes science and technology2018
Resistance to Acetaminophen Interference in a Novel Continuous Glucose Monitoring System.
Trial report in Journal of diabetes science and technology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
30 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Continuous Glucose Monitors and Automated Insulin Dosing Systems in the Hospital Consensus Guideline.Journal of diabetes science and technology · 2020Guideline
- Continuous Glucose Monitoring in General Wards for Prevention of Hypoglycemia: Results From the Glucose Telemetry System Pilot Study.Journal of diabetes science and technology · 2020Trial
- The Impact of Interfering Substances on Continuous Glucose Monitors: Part 4: Continuous Glucose Monitoring Interferents: In Vivo Performance, Clinical Implications and Future Standardization.Journal of diabetes science and technology · 2026Review
- The Impact of Interfering Substances on Continuous Glucose Monitors: Part 2: Marketed Continuous Glucose Monitoring Designs, Labeled Interfering Substances, and Design Mitigations.Journal of diabetes science and technology · 2026Review
- Accuracy of Dexcom G6 Pro and G7 Continuous Glucose Monitors in Patients Treated with Maintenance Dialysis.Diabetes technology & therapeutics · 2026Article
- Interference of Intravenous Acetaminophen with Continuous Glucose Monitoring System.JMA journal · 2025Article
- Dynamic Interference Testing-Unexpected Results Obtained with the Abbott Libre 2 and Dexcom G6 Continuous Glucose Monitoring Devices.Sensors (Basel, Switzerland) · 2025Article
- Review Article - Diabetes Technology in the Hospital: An Update.Current diabetes reports · 2024Review
- Laboratory Protocol and Pilot Results for Dynamic Interference Testing of Continuous Glucose Monitoring Sensors.Journal of diabetes science and technology · 2024Article
- Real-World Accuracy of a Continuous Glucose Monitoring System after Radiologic Exposure.Pediatric diabetes · 2024Article
- Interferences With CGM Systems: Practical Relevance?Journal of diabetes science and technology · 2022Article
- Making sense of glucose sensors in end-stage kidney disease: A review.Frontiers in clinical diabetes and healthcare · 2022Review
- Diabetes: the role of continuous glucose monitoring.Drugs in context · 2022Review
- Inaccurate Glucose Sensor Values After Hydroxyurea Administration.Diabetes technology & therapeutics · 2021Article
- Continuous Glucose Monitoring in the Hospital.Endocrinology and metabolism (Seoul, Korea) · 2021Review
- Effect of Repeated Doses of Acetaminophen on a Continuous Glucose Monitoring System with Permselective Membrane.Journal of diabetes science and technology · 2021Article
- Analysis of a Unique Postmarket Surveillance Dataset That a Glucose Test-Strip Demonstrates no Evidence of Interference and Robust Clinical Accuracy Irrespective of the Prescription Medication Status of a Large Cohort of Patients With Diabetes.Journal of diabetes science and technology · 2021Article
- COVID-19 outbreak and pediatric diabetes: Perceptions of health care professionals worldwide.Pediatric diabetes · 2020Article
- Glycemic Monitoring and Management in Advanced Chronic Kidney Disease.Endocrine reviews · 2020Review
- Implementation of Continuous Glucose Monitoring in the Hospital: Emergent Considerations for Remote Glucose Monitoring During the COVID-19 Pandemic.Journal of diabetes science and technology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Acetaminophen (APAP) can cause erroneously high readings in real-time continuous glucose monitoring (rtCGM) systems. APAP-associated bias in an investigational rtCGM system (G6) was evaluated by taking the difference in glucose measurements between rtCGM and YSI from 1 hour before to 6 hours after a 1-g oral APAP dose in 66 subjects with type 1 or type 2 diabetes. The interference effect was defined as the average post-dose (30-90 minutes) bias minus the average baseline bias for each subject. The clinically meaningful interference effect was defined as 10 mg/dL. The G6 system's overall mean (±SD) interference effect was 3.1 ± 4.8 mg/dL (one-sided upper 95% CI = 4.1 mg/dL), significantly lower than 10 mg/dL. The G6 system's resistance to APAP interference should provide reassurance to those using the drug.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.