Evidence map›Paper›PMID 29334524›Full record

ArticleMedical care2018

Leveraging Linkage of Cohort Studies With Administrative Claims Data to Identify Individuals With Cancer.

Mackenzie R Bronson, Nirav S Kapadia, Andrea M Austin, Qianfei Wang, Diane Feskanich, Julie P W Bynum, Francine Grodstein, Anna N A Tosteson

Abstract readComparative Study
In one paragraph

Article in Medical care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed.

  1. Cancer Risk With Advanced Therapies in Patients With Inflammatory Bowel Diseases: An Administrative Claims-Based Study.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Article
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  6. Review
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  8. Travel burden and bypassing closest site for surgical cancer treatment for urban and rural oncology patients.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2025
    Article
  9. Article
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  17. Association of rurality with utilization of palliative care and hospice among Medicare beneficiaries who died from pancreatic cancer: A cohort study.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mackenzie R BronsonThe Dartmouth Institute for Health Policy and Clinical Practice.
Nirav S KapadiaThe Dartmouth Institute for Health Policy and Clinical Practice.
Andrea M AustinThe Dartmouth Institute for Health Policy and Clinical Practice.
Qianfei WangThe Dartmouth Institute for Health Policy and Clinical Practice.
Diane FeskanichDepartment of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Julie P W BynumThe Dartmouth Institute for Health Policy and Clinical Practice.
Francine GrodsteinDepartment of Medicine, Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.
Anna N A TostesonThe Dartmouth Institute for Health Policy and Clinical Practice.

Funding

Translational Engineering in Cancer (TEC)P30CA023108 · NCI · DARTMOUTH COLLEGE · PI Steven D Leach · 1985 to 2026
$91.3M
Statistical MethodsP01CA087969 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI TWOROGER, SHELLEY S · 2000 to 2019
$77.8M
Long Term Multidisciplinary Study of Cancer in Women: The Nurses Health StudyUM1CA186107 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI ELIASSEN, A. HEATHER, STAMPFER, MEIR · 2014 to 2023
$22.3M
NCI NIH HHS P01 CA087969NCI NIH HHS P30 CA023108NCI NIH HHS UM1 CA186107
6 · The paper itself

Abstract

backgroundIn an effort to overcome quality and cost constraints inherent in population-based research, diverse data sources are increasingly being combined. In this paper, we describe the performance of a Medicare claims-based incident cancer identification algorithm in comparison with observational cohort data from the Nurses' Health Study (NHS).

methodsNHS-Medicare linked participants' claims data were analyzed using 4 versions of a cancer identification algorithm across 3 cancer sites (breast, colorectal, and lung). The algorithms evaluated included an update of the original Setoguchi algorithm, and 3 other versions that differed in the data used for prevalent cancer exclusions.

resultsThe algorithm that yielded the highest positive predictive value (PPV) (0.52-0.82) and κ statistic (0.62-0.87) in identifying incident cancer cases utilized both Medicare claims and observational cohort data (NHS) to remove prevalent cases. The algorithm that only used NHS data to inform the removal of prevalent cancer cases performed nearly equivalently in statistical performance (PPV, 0.50-0.79; κ, 0.61-0.85), whereas the version that used only claims to inform the removal of prevalent cancer cases performed substantially worse (PPV, 0.42-0.60; κ, 0.54-0.70), in comparison with the dual data source-informed algorithm.

conclusionsOur findings suggest claims-based algorithms identify incident cancer with variable reliability when measured against an observational cohort study reference standard. Self-reported baseline information available in cohort studies is more effective in removing prevalent cancer cases than are claims data algorithms. Use of claims-based algorithms should be tailored to the research question at hand and the nature of available observational cohort data.

Indexed as

Cohort StudiesAgedAged, 80 and overAlgorithmsBreast NeoplasmsColorectal NeoplasmsFemaleHumansInformation Storage and RetrievalInsurance Claim ReviewLung NeoplasmsMedicarePrevalenceUnited States

Identifiers

PMID29334524
PMCPMC6043405

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.