Evidence map›Paper›PMID 29334512›Full record

ArticleJournal of addiction medicine

Association Between Alcohol Use and Angina Symptoms Among Outpatients From the Veterans Health Administration.

Emily C Williams, Chris L Bryson, Haili Sun, David H Au, Katharine A Bradley

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of addiction medicine. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Emily C WilliamsHealth Services Research & Development (HSR&D), Center of Innovation for Veteran-Centered Value-Driven Care, Veterans Affairs (VA) Puget Sound Health Care System; Seattle, WA (ECW, CLB, HS, DHA, KAB); Department of Health Services, University of Washington, Seattle, WA (ECW, CLB, DHA, KAB); Department of Medicine, University of Washington, Seattle, WA (KAB); Kaiser Permanente Washington Health Research Institute, Seattle, WA (KAB).
Chris L Bryson
Haili Sun
David H Au
Katharine A Bradley
Health Services Research & Development · US

Funding

Training Clinicians in Implementation Research to Improve Alcohol-related CareK24AA022128 · NIAAA · KAISER FOUNDATION RESEARCH INSTITUTE · PI BRADLEY, KATHARINE ANTHONY · 2016 to 2020
$876k
Implementation Research for Evidence-based Care for Alcohol DependenceIK2HX001161 · VA · VA PUGET SOUND HEALTHCARE SYSTEM · PI WILLIAMS, EMILY CATERINA · 2015 to 2015
–
HSRD VA IK2 HX001161NIAAA NIH HHS K24 AA022128
6 · The paper itself

Abstract

backgroundAlcohol use is associated with angina incidence, but associations between alcohol use and experience of angina among patients with coronary artery disease (CAD) have not been described.

methodsOutpatients with CAD from 7 clinics in the Veterans Health Administration were surveyed; alcohol use was measured using the validated Alcohol Use Disorders Identification Test-Consumption scores categorized into 6 groups: nondrinking, low-risk drinking, and mild, moderate, severe, and very severe unhealthy alcohol use. Three domains of self-reported angina symptoms (frequency, stability, and physical function) were measured with the Seattle Angina Questionnaire. Linear regression models evaluated associations between alcohol use groups and angina symptoms. Models were adjusted first for age and then additionally for smoking, comorbidities, and depression.

resultsPatients (n = 8303) had a mean age of 66 years. In age-adjusted analyses, a U-shaped association was observed between alcohol use groups and all angina outcomes, with patients in nondrinking and severe unhealthy alcohol groups reporting the greatest angina symptoms and lowest functioning. After full adjustment, no clinically important and few statistically important differences were observed across alcohol use in angina stability or frequency. Patients in the nondrinking group had statistically greater functional limitation from angina than those in all groups of unhealthy alcohol use, though differences were small. Patients in all groups of unhealthy alcohol use did not differ significantly from those with low-risk drinking.

conclusionsAlcohol use was associated with some small statistically but no clinically important differences in angina symptoms among patients with CAD. This cross-sectional study does not support a protective effect of low-level drinking on self-reported angina.

Indexed as

AdultAgedAged, 80 and overAge DistributionAlcohol DrinkingAmbulatory CareAngina PectorisComorbidityCoronary Artery DiseaseCross-Sectional StudiesFemaleHumansIncidenceLinear ModelsMaleMiddle Aged

Identifiers

PMID29334512
PMCPMC5847476
OpenAlexW2784055293

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.