Evidence map›Paper›PMID 29334499›Full record

ArticleAlzheimer disease and associated disorders

Cognitive Function and its Risk Factors Among Older US Adults Living at Home.

William Dale, Ashwin A Kotwal, Joseph W Shega, L Philip Schumm, David W Kern, Jayant M Pinto, Kelly M Pudelek, Linda J Waite, Martha K McClintock

Abstract read
In one paragraph

Article in Alzheimer disease and associated disorders. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Observational
  8. Measuring Cognitive Function and Cognitive Decline With Response Time Data in the National Social Life, Health, and Aging Project.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  9. Social Connectedness of Older Adults During the COVID-19 Pandemic: Evidence by Survey Mode and Respondent Dementia.The journals of gerontology. Series B, Psychological sciences and social sciences · 2025
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Association ofNeurology · 2023
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

William DaleDepartment of Supportive Care Medicine, City of Hope Medical Center, Duarte, CA.
Ashwin A KotwalDepartment of Medicine, Brigham and Women's Hospital, Harvard University, Boston, MA.
Joseph W ShegaVitas Hospice, Miami, FL.
L Philip SchummDepartments of Public Health Sciences.
David W KernCollege of Arts and Sciences, Northeastern Illinois University.
Jayant M PintoOtolaryngology.
Kelly M PudelekNORC at the University of Chicago, Chicago, IL.
Linda J WaiteSociology.
Martha K McClintockComparative Human Development and Institute for Mind and Biology, University of Chicago.

Funding

National Social Life, Health and Aging: Wave 4R01AG043538 · NIA · NATIONAL OPINION RESEARCH CENTER · PI LINDA J WAITE · 2013 to 2026
$42.7M
National Social Life, Health, and Aging Project: Anaylsis of Wave 1 and Wave 2R37AG030481 · NIA · NATIONAL OPINION RESEARCH CENTER · PI WAITE, LINDA J · 2008 to 2017
$15.4M
National Social Life, Health and Aging Project (RMI)R01AG021487 · NIA · NATIONAL OPINION RESEARCH CENTER · PI WAITE, LINDA J · 2003 to 2007
$12.2M
NSHAP Wave II Partner Data CollectionR01AG033903 · NIA · NATIONAL OPINION RESEARCH CENTER · PI WAITE, LINDA J · 2009 to 2013
$5.8M
NIA NIH HHS R01 AG021487NIA NIH HHS R01 AG033903NIA NIH HHS R01 AG043538NIA NIH HHS R37 AG030481
6 · The paper itself

Abstract

backgroundThe Montreal Cognitive Assessment (MoCA) has not been administered to a representative national sample, precluding comparison of patient scores to the general population and for risk factor identification.

methodsA validated survey-based adaptation of the MoCA (MoCA-SA) was administered to a probability sample of home-dwelling US adults aged 62 to 90, using the National Social Life, Health, and Aging Project (n=3129), yielding estimates of prevalence in the United States. The association between MoCA-SA scores and sociodemographic and health-related risk factors were determined.

resultsMoCA-SA scores decreased with age, and there were substantial differences among sex, education, and race/ethnicity groups. Poor physical health, functional status, and depression were also associated with lower cognitive performance; current health behaviors were not. Using the recommended MoCA cut-point score for Mild Cognitive Impairment (MoCA score <26; MoCA-SA score <17), 72% (95% confidence interval, 69% to 74%) of older US adults would be classified as having some degree of cognitive impairment.

conclusionsOur results provide an important national estimate for interpreting MoCA scores from individual patients, and establish wide variability in cognition among older home-dwelling US adults. Care should be taken in applying previously-established MoCA cut-points to the general population, especially when evaluating individuals from educationally and ethnically diverse groups.

Indexed as

Independent LivingActivities of Daily LivingAgedCognitionFemaleGeriatric AssessmentHumansMaleNeuropsychological TestsRisk FactorsSurveys and Questionnaires

Identifiers

PMID29334499
PMCPMC6728147

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.