Evidence map›Paper›PMID 29333664›Full record

ArticleAddiction (Abingdon, England)2018

Increased non-fatal overdose risk associated with involuntary drug treatment in a longitudinal study with people who inject drugs.

Claudia Rafful, Ricardo Orozco, Gudelia Rangel, Peter Davidson, Dan Werb, Leo Beletsky, Steffanie A Strathdee

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
8.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

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  16. Opinion: Public health and police: Building ethical and equitable opioid responses.Proceedings of the National Academy of Sciences of the United States of America · 2021
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 4 countries.

Claudia RaffulDivision of Global Public Health, School of Medicine, University of California, San Diego, CA, USA.ORCID 0000-0003-0083-7276
Ricardo OrozcoNational Institute of Psychiatry, México City, Mexico.ORCID 0000-0002-6580-585X
Gudelia RangelSecretariat of Health, Mexico City, Mexico.
Peter DavidsonDivision of Global Public Health, School of Medicine, University of California, San Diego, CA, USA.
Dan WerbDivision of Global Public Health, School of Medicine, University of California, San Diego, CA, USA.
Leo BeletskyDivision of Global Public Health, School of Medicine, University of California, San Diego, CA, USA.
Steffanie A StrathdeeDivision of Global Public Health, School of Medicine, University of California, San Diego, CA, USA.
St. Michael's Hospital · CAUniversity of California System · USNortheastern University · USSecretaria de Salud · MX

Funding

Impact of Drug Policy Reform on the HIV Risk Environment among IDUs in TijuanaR37DA019829 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STRATHDEE, STEFFANIE A. · 2010 to 2019
$6.7M
Police Training to Reduce Occupational Needlesticks and HIV among Substance UsersR01DA039073 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BELETSKY, LEO, STRATHDEE, STEFFANIE A. · 2015 to 2019
$3.2M
Interdisciplinary Research Training Institute on Hispanic Drug AbuseR25DA026401 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI VALDEZ, AVELARDO · 2009 to 2019
$3.2M
Preventing HIV by modifying the context for injecting initiationDP2DA040256 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI WERB, DANIEL M · 2015 to 2015
$2.3M
AIDS International Training Program in the US Mexico Border RegionD43TW008633 · FIC · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI STRATHDEE, STEFFANIE A. · 2010 to 2014
$1.5M
FIC NIH HHS D43 TW008633NIDA NIH HHS DP2 DA040256NIDA NIH HHS R01 DA039073NIDA NIH HHS R25 DA026401NIDA NIH HHS R37 DA019829
6 · The paper itself

Abstract

aimTo assess the effect of involuntary drug treatment (IDT) on non-fatal overdose among people who inject drugs (PWID).

designLongitudinal study.

settingTijuana, Mexico.

participantsBaseline sample of 671 PWID included 258 (38.4%) women and 413 (61.6%) men. MEASUREMENTS: Primary independent variables were reported recent (i.e. past 6 months) non-fatal overdose event (dependent variable) and IDT. Substance use the day of the non-fatal overdose was also examined.

findingsFrom 2011 to 2017, 213 participants (31.7%) reported a recent non-fatal overdose and 103 (15.4%) reported recent IDT. Heroin, in combination with methamphetamine and tranquilizers, were the drugs most reported at the day of the event. IDT significantly increased the odds of reporting a non-fatal overdose event [adjusted odds ratio (aOR) = 1.76; 95% confidence interval (CI) = 1.04-2.96]. Odds of non-fatal overdose also increased independently for each additional injection per day (aOR = 1.05; 95% CI = 1.02-1.08), recent tranquilizer use (aOR = 1.92; 95% CI = 1.41-2.61) and using hit doctors (aOR = 1.68; 95% CI = 1.29-2.18) and decreased with age (aOR = 0.97 per year, 95% CI = 0.95-0.99).

conclusionsRecent involuntary drug treatment in Mexico is a risk factor for non-fatal drug overdose.

Indexed as

AdultCentral Nervous System StimulantsDrug OverdoseFemaleHeroinHumansInvoluntary TreatmentLongitudinal StudiesMaleMethamphetamineMexicoNarcoticsRisk FactorsSubstance Abuse, IntravenousTranquilizing AgentsCentral Nervous System StimulantsHeroinMethamphetamineNarcoticsTranquilizing AgentsCohort studygeneralized estimating equationinvoluntary treatmentnon-fatal overdosepeople who inject drugsTijuana

Identifiers

PMID29333664
PMCPMC5938130
OpenAlexW2784197732

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.