ArticleJournal of clinical laboratory analysis2018
Determination of vitamins K
Article in Journal of clinical laboratory analysis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 38 citations in OpenAlex.
- Associations between maternal circulating vitamin K isoforms and adverse pregnancy events.BMC pregnancy and childbirth · 2026Article
- Spectrofluorophotometric Analysis of Phytoconstituents, Biomarkers, Enzyme Kinetics and Trace Metals: A Comprehensive Review.Journal of fluorescence · 2025Review
- Vitamin K and women's health: a review.Frontiers in global women's health · 2025Review
- A preliminary study on the reference intervals of vitamin K in some areas of Beijing with normal physical examination population.Journal of nutritional science · 2025Article
- Quantitative Study of Vitamin K in Plants by Pressurized Liquid Extraction and LC-MS/MS.Molecules (Basel, Switzerland) · 2024Article
- The investigation of connection between anticoagulant therapy and vitamin K homologues in human determined by LC-MS/MS.Bioanalysis · 2024Article
- Vitamin K and Calcium Chelation in Vascular Health.Biomedicines · 2023Review
- Development, Validation, and Two-Year Application of Rapid and Simple LC-MS/MS-Based Method for the Determination of K2MK-7 in Blood Samples.Molecules (Basel, Switzerland) · 2023Article
- Article
- Role of Vitamin K in Bone and Muscle Metabolism.Calcified tissue international · 2023Review
- Boosting vegetation, biochemical constituents, grain yield and anti-cancer performance of cultivated oat (Avena sativa L) in calcareous soil using oat extracts coated inside nanocarriers.BMC plant biology · 2022Article
- [Serum vitamin KZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2022Article
- Vitamin K - sources, physiological role, kinetics, deficiency, detection, therapeutic use, and toxicity.Nutrition reviews · 2022Review
- Review
- A concise review of quantification methods for determination of vitamin K in various biological matrices.Journal of pharmaceutical and biomedical analysis · 2019Review
- Article
- Determination of vitamins KJournal of clinical laboratory analysis · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNew high-performance liquid chromatography (HPLC) method was developed for the determination of vitamin K
methodsVitamin K was determined by HPLC with fluorescence detection after postcolumn zinc reduction. The detection was performed at 246 nm (excitation) and 430 nm (emission). The internal standard and 2 mL of ethanol were added to 500 μL of serum. The mixture was extracted with 4 mL of hexane, and solid phase extraction was then used.
resultsThe HLPC method was fully validated. The intra- and interday accuracy and precision were evaluated on two QC samples by multiple analysis, and CV were less than 10%. The limit of quantification for MK-4 was found at 0.04 ng/mL, for K
conclusionNew HPLC method for the determination of vitamins K
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.