Evidence map›Paper›PMID 29333428›Full record

ArticleCanadian journal of gastroenterology & hepatology2017

The Effect of Prucalopride on Small Bowel Transit Time in Hospitalized Patients Undergoing Capsule Endoscopy.

Majid Alsahafi, Paula Cramer, Nazira Chatur, Fergal Donnellan

Open access · goldAbstract readEvaluation Study
In one paragraph

Article in Canadian journal of gastroenterology & hepatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Gastrointestinal dysfunction in the synucleinopathies.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2021
    Review
  6. The impact of inpatient capsule endoscopy on the need for therapeutic interventions in patients with obscure gastrointestinal bleeding.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Majid AlsahafiDivision of Gastroenterology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0002-9076-536X
Paula CramerDivision of Gastroenterology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.
Nazira ChaturDivision of Gastroenterology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.
Fergal DonnellanDivision of Gastroenterology, Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0001-9428-0864
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The inpatient status is a well-known risk factor for incomplete video capsule endoscopy (VCE) examinations due to prolonged transit time. We aimed to evaluate the effect of prucalopride on small bowel transit time for hospitalized patients undergoing VCE. Methods: We included all hospitalized patients who underwent VCE at a tertiary academic center from October 2011 through September 2016. A single 2 mg dose of prucalopride was given exclusively for all patients who underwent VCE between March 2014 and December 2015. VCE studies were excluded if the capsule was retained or endoscopically placed, if other prokinetic agents were given, in cases with technical failure, or if patients had prior gastric or small bowel resection. Results: 442 VCE were identified, of which 68 were performed in hospitalized patients. 54 inpatients were included, of which 29 consecutive patients received prucalopride. The prucalopride group had a significantly shorter small bowel transit time compared to the control group (92 versus 275.5, Conclusions: Our results suggest that the administration of prucalopride prior to VCE is a simple and effective intervention to decrease small bowel transit time.

Indexed as

AgedBenzofuransCapsule EndoscopyFemaleGastrointestinal AgentsGastrointestinal TransitHospitalizationHumansInpatientsIntestine, SmallMaleMiddle AgedProspective StudiesRetrospective StudiesTime FactorsTreatment OutcomeBenzofuransGastrointestinal Agentsprucalopride

Identifiers

PMID29333428
PMCPMC5733169
OpenAlexW2768516314

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.