ArticleMRS communications2017
Next Generation Tissue Engineering of Orthopedic Soft Tissue-to-Bone Interfaces.
Article in MRS communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Anatomical design and production of a novel three-dimensional co-culture system replicating the human flexor digitorum profundus enthesis.Journal of anatomy · 2026Article
- Higher arterial supply in the distal quadriceps tendon: Results from 7-Tesla quantitative magnetic resonance imaging, histology and high-resolution computed tomography.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2026Article
- Integrating Modern Technologies into Traditional Anterior Cruciate Ligament Tissue Engineering.Bioengineering (Basel, Switzerland) · 2025Review
- Gradient scaffolds in bone-soft tissue interface engineering: Structural characteristics, fabrication techniques, and emerging trends.Journal of orthopaedic translation · 2025Review
- Biomimetic Approaches for the Design and Fabrication of Bone-to-Soft Tissue Interfaces.ACS biomaterials science & engineering · 2023Review
- 3D Bioelectronics with a Remodellable Matrix for Long-Term Tissue Integration and Recording.Advanced materials (Deerfield Beach, Fla.) · 2023Article
- ACL microtrauma: healing through nutrition, modified sports training, and increased recovery time.Journal of experimental orthopaedics · 2022Review
- Engineering Heart Valve Interfaces Using Melt Electrowriting: Biomimetic Design Strategies from Multi-Modal Imaging.Advanced healthcare materials · 2022Article
- Engineering an enthesis-like graft for rotator cuff repair: An approach to fabricate highly biomimetic scaffold capable of zone-specifically releasing stem cell differentiation inducers.Bioactive materials · 2022Article
- Biodegradable Polyphosphazenes for Regenerative Engineering.Journal of materials research · 2022Article
- Joining soft tissues to bone: Insights from modeling and simulations.Bone reports · 2021Review
- Tissue Engineering for the Insertions of Tendons and Ligaments: An Overview of Electrospun Biomaterials and Structures.Frontiers in bioengineering and biotechnology · 2021Review
- Segmentally Demineralized Cortical Bone With Stem Cell-Derived Matrix Promotes Proliferation, Migration and Differentiation of Stem CellsFrontiers in cell and developmental biology · 2021Article
- Designing a novel vacuum aspiration system to decellularize large-size enthesis with preservation of physicochemical and biological properties.Annals of translational medicine · 2020Article
- Mineral Distribution Spatially Patterns Bone Marrow Stromal Cell Behavior on Monolithic Bone Scaffolds.Acta biomaterialia · 2020Article
- Robust phenotypic maintenance of limb cells during heterogeneous culture in a physiologically relevant polymeric-based constructed graft system.Scientific reports · 2020Article
- Three-dimensional printed multiphasic scaffolds with stratified cell-laden gelatin methacrylate hydrogels for biomimetic tendon-to-bone interface engineering.Journal of orthopaedic translation · 2020Article
- Understanding the Stiff-to-Compliant Transition of the Meniscal Attachments by Spatial Correlation of Composition, Structure, and Mechanics.ACS applied materials & interfaces · 2019Article
- Top-down Fabrication of Spatially Controlled Mineral-Gradient Scaffolds for Interfacial Tissue Engineering.ACS biomaterials science & engineering · 2019Article
- Cellular and Chemical Gradients to Engineer the Meniscus-to-Bone Insertion.Advanced healthcare materials · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Soft tissue-to-bone interfaces are complex structures that consist of gradients of extracellular matrix materials, cell phenotypes, and biochemical signals. These interfaces, called entheses for ligaments, tendons, and the meniscus, are crucial to joint function, transferring mechanical loads and stabilizing orthopedic joints. When injuries occur to connected soft tissue, the enthesis must be re-established to restore function, but due to structural complexity, repair has proven challenging. Tissue engineering offers a promising solution for regenerating these tissues. This prospective review discusses methodologies for tissue engineering the enthesis, outlined in three key design inputs: materials processing methods, cellular contributions, and biochemical factors.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.