Evidence map›Paper›PMID 29333295›Full record

ArticleInternational journal of nephrology2017

Serial Galactose-Deficient IgA1 Levels in Children with IgA Nephropathy and Healthy Controls.

John T Sanders, M Colleen Hastings, Zina Moldoveanu, Jan Novak, Bruce A Julian, Zoran Bursac, Robert J Wyatt

Open access · goldAbstract read
In one paragraph

Article in International journal of nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. [Value of galactose-deficient IgA1 in the early diagnosis of Henoch-Schönlein purpura nephritis in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2019
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

John T SandersSanford Children's Hospital, Sioux Falls, SD 57117, USA.
M Colleen HastingsUniversity of Tennessee Health Sciences Center, Memphis, TN 38013, USA.
Zina MoldoveanuUniversity of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-5372-5262
Jan NovakUniversity of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-9211-6670
Bruce A JulianUniversity of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0001-5781-1021
Zoran BursacUniversity of Tennessee Health Sciences Center, Memphis, TN 38013, USA.ORCID 0000-0001-9306-0907
Robert J WyattUniversity of Tennessee Health Sciences Center, Memphis, TN 38013, USA.ORCID 0000-0001-6077-0259
University of Alabama at Birmingham · USUniversity of Tennessee Health Science Center · USSanford Children's Specialty Clinic · US

Funding

USE OF MOTIVATIONAL INTERVIEWING TO MANAGE TYPE I DIABETESM01RR000211 · NCRR · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI HAK, EMILY B · 1985 to 2006
$9.6M
Elucidating IgA Nephropathy through Genetic Studies of IgA1 GlycosylationR01DK082753 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI GHARAVI, ALI G, NOVAK, JAN · 2009 to 2024
$8.7M
Molecular Basis of Pathogenicity of IgA1-containing Immune ComplexesR01DK078244 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI JAN NOVAK · 2007 to 2026
$6.0M
NCRR NIH HHS M01 RR000211NIDDK NIH HHS R01 DK078244NIDDK NIH HHS R01 DK082753
6 · The paper itself

Abstract

Galactose-deficient IgA1 (Gd-IgA1) is a key pathogenic factor for IgA nephropathy (IgAN) and a potential biomarker for the disease. This study examined serial serum Gd-IgA1 levels over 1 year in 13 children with IgAN and 40 healthy children, to determine whether or not serum Gd-IgA1 levels changed over time. Subjects were younger than 18 years of age. Follow-up measurements were scheduled 6 and/or 12 months later. Analysis of variance and regression models for repeated measures were used to estimate group and time effects. Serum Gd-IgA1 level was higher in initial samples for IgAN patients compared to those of healthy children (

Identifiers

PMID29333295
PMCPMC5733148
OpenAlexW2770344294

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.