Evidence map›Paper›PMID 29333256›Full record

ReviewF1000Research2017

Pathophysiology and treatment of patients with beta-thalassemia - an update.

Eitan Fibach, Eliezer A Rachmilewitz

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in F1000Research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03948737 (The Effect of Alpha-tocopherol in Hemolysis and Oxidative Stress Marker on the Red Cell), which is not on this map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03948737 nacompletednot on this map

The Effect of Alpha-tocopherol in Hemolysis and Oxidative Stress Marker on the Red Cell

TypeinterventionalSponsorIndonesia UniversityRan2016 to 2017Enrolled40ConditionsBeta Thalassemia Major Anemia, Hemolysis, Oxidative StressArmsAlpha-Tocopherol, Placebo oral tablet
3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 84 citations in OpenAlex.

  1. Trial
  2. Article
  3. Sex determines cardiac and renal Vulnerability to chronic hemoglobin toxicity.Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2026
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Assessment of Serum Autophagy Related Protein Beclin-1 in Egyptian Adult Beta Thalassemia Patients.Indian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2025
    Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Eitan FibachDepartment of Hematology, Hadassah - Hebrew University Medical Center, Jerusalem, Israel.ORCID https://orcid.org/0000-0002-6658-6126
Eliezer A RachmilewitzDepartment of Hematology, The Edith Wolfson Medical Center, Holon, Israel.
Hadassah Medical Center · ILWolfson Medical Center · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thalassemia (thal) is an autosomal recessive, hereditary, chronic hemolytic anemia due to a partial or complete deficiency in the synthesis of α-globin chains (α-thal) or β-globin chains (β-thal) that compose the major adult hemoglobin (α

Indexed as

hemolytic anemiaThalessemiaβ-globin

Identifiers

PMID29333256
PMCPMC5749127
OpenAlexW2778650554

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.