ArticleRadiology and oncology2017
Minimally Invasive Electrochemotherapy Procedure for Treating Nasal Duct Tumors in Dogs using a Single Needle Electrode.
Article in Radiology and oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 35 citations in OpenAlex.
- Case Report: Endoscopic-guided electrochemotherapy combined with metronomic chemotherapy for the treatment of nasal tumors in dogs.Frontiers in veterinary science · 2026Article
- Feline Injection-Site Sarcoma Treated with Surgery, Orthovoltage Radiotherapy, and Electrochemotherapy. A Retrospective Series of 72 Cases.Bioelectricity · 2025Article
- Clinical outcomes and prognostic factors of repeated conventional hypofractionated radiotherapy for recurrent intranasal tumors in dogs.Open veterinary journal · 2025Article
- Palliative endoscopic debulking treatment of canine nasal carcinoma - 35 cases (2016 to 2019): A retrospective multicentric study.The Canadian veterinary journal = La revue veterinaire canadienne · 2025Article
- Computed Tomography-Guided Radiofrequency Ablation of Nasal Carcinomas in Dogs.Animals : an open access journal from MDPI · 2024Article
- Evaluation of the safety and feasibility of electrochemotherapy with intravenous bleomycin as local treatment of bladder cancer in dogs.Scientific reports · 2023Article
- Electrochemotherapy: An Alternative Strategy for Improving Therapy in Drug-Resistant SOLID Tumors.Cancers · 2022Review
- Electrochemotherapy treatment safety under parallel needle deflection.Scientific reports · 2022Article
- Veterinary Guidelines for Electrochemotherapy of Superficial Tumors.Frontiers in veterinary science · 2022Article
- Review
- A Retrospective Multicentric Study of Electrochemotherapy in the Treatment of Feline Nasal Planum Squamous Cell Carcinoma.Veterinary sciences · 2021Article
- Article
- Electroporation as the Immunotherapy Strategy for Cancer in Veterinary Medicine: State of the Art in Latin America.Vaccines · 2020Review
- Electrochemotherapy in treatment of canine oral malignant melanoma and factors influencing treatment outcome.Radiology and oncology · 2020Article
- Electroporation-Based Treatments in Small Animal Veterinary Oral and Maxillofacial Oncology.Frontiers in veterinary science · 2020Review
- Recent Advances in Electrochemotherapy.Bioelectricity · 2019Review
- Electroporation optimizes the uptake of boron-10 by tumor for boron neutron capture therapy (BNCT) mediated by GB-10: a boron biodistribution study in the hamster cheek pouch oral cancer model.Radiation and environmental biophysics · 2019Article
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNasal cavity tumors are usually diagnosed late, when they already have infiltrated adjacent tissues thus requiring very aggressive treatments with serious side effects. Here we use electrochemotherapy (ECT), a well demonstrated treatment modality for superficial tumors. MATERIALS AND
methodsIn the case of deep-seated tumors, the main limitation of ECT is reaching the tumor with an appropriate electric field. To overcome this limitation we introduce the single needle electrode (SiNE), a minimally invasive device that can deliver an appropriate electric field with a simple procedure. Twenty-one canine patients with spontaneous tumors were selected, eleven were treated using the SiNE with ECT, and ten with surgery plus adjuvant chemotherapy as a control group.
resultsIn the SiNE group, 27% achieved a complete response, 64% had a partial response, and 9% had a stable disease. This means that 91% of objective responses were obtained. The mean overall survival was 16.86 months (4-32 months, median 16.5 months), with a survival rate significantly higher (p = 0.0008) when compared with control group. The only side effect observed was the inflammation of the treated nasal passage, which was controlled with corticosteroid therapy for one week. One year after the treatment, 60% of the canine of the SiNE group vs. 10% of the control group remained alive, and after the 32 months follow-up, the survival rate were 30% and 0%, respectively.
conclusionsECT with the SiNE can be safely used in canine to treat nasal tumors with encouraging results.
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