Evidence map›Paper›PMID 29333070›Full record

ArticleAnnals of gastroenterology

Bacterial infections in patients with liver cirrhosis: clinical characteristics and the role of C-reactive protein.

Melanie Deutsch, Spilios Manolakopoulos, Ioannis Andreadis, Markos Giannaris, George Kontos, Hariklia Kranidioti, Maria Pirounaki, John Koskinas

Open access · diamondAbstract read
In one paragraph

Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Melanie Deutsch2 Academic Department of Internal Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.
Spilios Manolakopoulos2 Academic Department of Internal Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.
Ioannis Andreadis2 Academic Department of Internal Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.
Markos Giannaris2 Academic Department of Internal Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.
George Kontos2 Academic Department of Internal Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.
Hariklia Kranidioti2 Academic Department of Internal Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.
Maria Pirounaki2 Academic Department of Internal Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.
John Koskinas2 Academic Department of Internal Medicine, National and Kapodistrian University of Athens, Hippokration General Hospital, Athens, Greece.
Hippocration General Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe diagnosis of bacterial infection in cirrhotic patients may be difficult, because of the absence of classical signs such as fever and raised white blood cell count. The role of C-reactive protein (CRP) in this context has not been clearly defined.

methodsClinical and laboratory characteristics of 210 consecutive cirrhotic patients with (n=100) or without (n=110) bacterial infection were compared with a control group of non-cirrhotic patients with infection (n=106).

resultsSignificantly fewer patients with cirrhosis had a body temperature ≥37°C when presenting with bacterial infection (56% cirrhotic vs. 85.5% non-cirrhotic patients, P=0.01). Mean leukocyte count was 6.92 × 10

conclusionsCRP at admission could help diagnose infection in cirrhotic patients. Since the severity of liver disease seems to affect the CRP values, lower CRP levels might indicate infection. Clinical suspicion is necessary to avoid delay in diagnosis and initiate antibiotic treatment.

Indexed as

Bacterial infectionC-reactive proteinliver cirrhosis

Identifiers

PMID29333070
PMCPMC5759615
OpenAlexW2766302766

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.