Evidence map›Paper›PMID 29332677›Full record

Trial reportSleep health2018

Pilot study of sleep and meal timing effects, independent of sleep duration and food intake, on insulin sensitivity in healthy individuals.

Theresa Pizinger, Kyle Kovtun, Arindam RoyChoudhury, Blandine Laferrère, Ari Shechter, Marie-Pierre St-Onge

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Sleep health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Cognitive benefits of sleep: a narrative review to explore the relevance of glucose regulation.Sleep advances : a journal of the Sleep Research Society · 2025
    Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Theresa PizingerNew York Obesity Nutrition Research Center, Department of Medicine, Columbia University Medical Center, New York, NY.
Kyle KovtunNew York Obesity Nutrition Research Center, Department of Medicine, Columbia University Medical Center, New York, NY.
Arindam RoyChoudhuryDivision of Biostatistics and Epidemiology, Department of Healthcare Policy and Research, Weill Cornell Medicine, Cornell University, New York, NY.
Blandine LaferrèreNew York Obesity Nutrition Research Center, Department of Medicine, Columbia University Medical Center, New York, NY.
Ari ShechterNew York Obesity Nutrition Research Center, Department of Medicine, Columbia University Medical Center, New York, NY.
Marie-Pierre St-OngeNew York Obesity Nutrition Research Center, Department of Medicine, Columbia University Medical Center, New York, NY; Institute of Human Nutrition, Columbia University Medical Center, New York, NY. Electronic address: ms2554@cumc.columbia.edu.
Columbia University Irving Medical Center · USCornell University · US

Funding

RESEARCH TRAININGP30DK026687 · NIDDK · ST. LUKE'S-ROOSEVELT INST FOR HLTH SCIS · PI Anthony W Ferrante, DYMPNA GALLAGHER · 1986 to 2026
$33.0M
Clinical and Translational Science AwardUL1TR000040 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI GINSBERG, HENRY N · 2012 to 2015
$26.2M
Impact of sleep and meal timing on food intake regulation.R56HL119945 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ST-ONGE, MARIE-PIERRE · 2014 to 2014
$682k
NCATS NIH HHS UL1 TR000040NHLBI NIH HHS R56 HL119945NIDDK NIH HHS P30 DK026687
6 · The paper itself

Abstract

This pilot study tested the independent and interactive effects of sleep and meal times, under identical sleep duration and feeding conditions, on insulin sensitivity (Si) in overweight adults. Participants underwent a 4-phase randomized crossover inpatient study differing in sleep times: normal (Ns: 0000-0800 hours) or late (Ls: 0330-1130 hours); and in meal times: normal (Nm: 1, 5, 11, and 12.5 hours after awakening) or late (Lm: 4.5, 8.5, 14.5, and 16 hours after awakening). An insulin-modified frequently sampled intravenous glucose tolerance test, at scheduled breakfast time, and a meal tolerance test, at scheduled lunch time, were performed to assess Si after 3 days in each condition. Six participants were enrolled (4 men, 2 women; mean age 25.1±[SD] 3.9 years, body mass index 29.2±2.7 kg/m

Indexed as

AdultEatingFemaleGlucose Tolerance TestHumansInsulinInsulin ResistanceMaleMealsMiddle AgedPilot ProjectsSleepTime FactorsYoung AdultInsulinCortisolGlucose toleranceInsulin sensitivityMeal timingMelatoninSleep timing

Identifiers

PMID29332677
PMCPMC5771427
OpenAlexW2770107627

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.