ArticleSleep health2018
Sleep apnea and pesticide exposure in a study of US farmers.
Article in Sleep health, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Is exposure to chemical pollutants associated with sleep outcomes? A systematic review.Sleep medicine reviews · 2023Pooled it
- Climate Change and Respiratory Health: Opportunities to Contribute to Environmental Justice: An Official American Thoracic Society Workshop Report.Annals of the American Thoracic Society · 2025Article
- Article
- Pyridostigmine Bromide Pills and Pesticides Exposure as Risk Factors for Eye Disease in Gulf War Veterans.Journal of clinical medicine · 2023Article
- Urinary phthalates, phenols, and parabens in relation to sleep health markers among a cohort of Mexican adolescents.The Science of the total environment · 2023Article
- Occupational Exposure to Pesticides as a Risk Factor for Sleep Disorders.International journal of environmental research and public health · 2023Article
- Potential Effects on Mental Health Status Associated with Occupational Exposure to Pesticides among Thai Farmers.International journal of environmental research and public health · 2022Article
- Prenatal maternal pesticide exposure in relation to sleep health of offspring during adolescence.Environmental research · 2022Article
- Association between pesticide exposure and sleep health among a representative sample of US adults: evidence from NHANES 2009-2014.BMC public health · 2021Article
- Health problems in agricultural workers occupationally exposed to pesticides.Revista brasileira de medicina do trabalho : publicacao oficial da Associacao Nacional de Medicina do Trabalho-ANAMT · 2021Review
- Pharmacological Actions of Carbamate Insecticides at Mammalian Melatonin Receptors.The Journal of pharmacology and experimental therapeutics · 2021Article
- Occupational exposure to pesticides and associated health effects among greenhouse farm workers.Environmental science and pollution research international · 2020Review
- Relationship between cumulative exposure to pesticides and sleep disorders among greenhouse vegetable farmers.BMC public health · 2019Article
- Comparison of Self-Rated Health among Characteristic Groups of Vegetable Greenhouse Farmers Based on Exposure to Pesticide Residuals: A Latent Profile Analysis.BioMed research international · 2019Article
Corrections and comments
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Authors and funding
11 authors at 5 institutions in 1 country.
Funding
Abstract
introductionCarbamate and organophosphate pesticides inhibit acetylcholinesterase, and poisoning leads to respiratory depression. Thus, involvement in sleep apnea is plausible, but no data exist at lower levels of exposure. Other pesticides could impact sleep apnea by different mechanisms but have not been studied. Our study examines the associations between pesticide exposure and sleep apnea among pesticide applicators from a US farming population. PARTICIPANTS AND
methodsWe analyzed data from 1569 male pesticide applicators, mostly farmers, from an asthma case-control study nested within the prospective Agricultural Health Study. On questionnaires, participants reported use of specific pesticides and physician diagnosis plus prescribed treatments for sleep apnea. We used multivariable logistic regression to estimate associations between ever use of 63 pesticides and sleep apnea (234 cases, 1335 noncases).
resultsThe most notable association was for carbofuran, a carbamate (100 exposed cases, odds ratio 1.83, 95% confidence interval 1.34-2.51, P=.0002). Carbofuran use began before reported onset of sleep apnea in all cases. DISCUSSION: This study adds to the known adverse health outcomes of exposure to carbofuran, a pesticide canceled in the United States in 2009 for most agricultural purposes but persists in the environment and remains in use in some other countries.
conclusionsWe conducted the first epidemiological study investigating the association of pesticide exposure and sleep apnea. Our results in a male agricultural population suggests that exposure to carbofuran is positively associated with sleep apnea.
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