ArticleNeuromolecular medicine2018
Behavioral, Biochemical and Molecular Characterization of a Parkinson's Disease Mouse Model Using the Neurotoxin 2'-CH
Alice Laschuk Herlinger, Agihane Rodrigues Almeida, Sarah Martins Presti-Silva, Evaldo Vitor Pereira, Filipe Andrich, Rita Gomes Wanderley Pires, Cristina Martins-Silva
Abstract read
In one paragraphArticle in Neuromolecular medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 48% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
3 · Its place in the literatureWho cites it
0 citing papers in PubMed, 3 citations in OpenAlex.
No citing paper in PubMed yet.
4 · The recordCorrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what moneyAuthors and funding
7 authors at 2 institutions in 1 country.
Alice Laschuk HerlingerLaboratory of Molecular and Behavioral Neurobiology, Health Sciences Center, Federal University of Espirito Santo, Vitoria, ES, Brazil. alaschuk@gmail.com.
Agihane Rodrigues AlmeidaLaboratory of Molecular and Behavioral Neurobiology, Health Sciences Center, Federal University of Espirito Santo, Vitoria, ES, Brazil.
Sarah Martins Presti-SilvaLaboratory of Molecular and Behavioral Neurobiology, Health Sciences Center, Federal University of Espirito Santo, Vitoria, ES, Brazil.
Evaldo Vitor PereiraGraduate Program in Biochemistry and Pharmacology, Health Sciences Center, Federal University of Espirito Santo, Vitoria, ES, Brazil.
Filipe AndrichLaboratory of Molecular and Behavioral Neurobiology, Health Sciences Center, Federal University of Espirito Santo, Vitoria, ES, Brazil.
Rita Gomes Wanderley PiresLaboratory of Molecular and Behavioral Neurobiology, Health Sciences Center, Federal University of Espirito Santo, Vitoria, ES, Brazil.
Cristina Martins-SilvaLaboratory of Molecular and Behavioral Neurobiology, Health Sciences Center, Federal University of Espirito Santo, Vitoria, ES, Brazil.
Universidade Federal do Espírito Santo · BRUniversidade Federal do Rio de Janeiro · BR
Funding
Conselho Nacional de Desenvolvimento Científico e Tecnológico 479243/2013-1Fundação Estadual de Amparo à Pesquisa do Estado do Espírito Santo 0603/2015
6 · The paper itselfAbstract
The neurotoxin MPTP has long been used to create a mouse model of Parkinson's disease (PD). Indeed, several MPTP analogues have been developed, including 2'-CH
Indexed as
Neurotoxins1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine3,4-Dihydroxyphenylacetic AcidAnimalsCorpus StriatumDisease Models, AnimalDopamineDopamine Plasma Membrane Transport ProteinsExploratory BehaviorGene Expression RegulationHand StrengthHomovanillic AcidMaleMiceMice, Inbred C57BLMonoamine Oxidase1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine3,4-Dihydroxyphenylacetic AcidDopamineDopamine Plasma Membrane Transport ProteinsHomovanillic AcidMonoamine OxidaseNerve Tissue ProteinsNeurotoxins2′-CH3-MPTPGene expressionMotor behaviorParkinson’s disease
Identifiers
PMID29332269
OpenAlexW2783356666
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