Evidence map›Paper›PMID 29332241›Full record

SynthesisJournal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing2018

Atrial fibrillation is associated with sudden cardiac death: a systematic review and meta-analysis.

Pattara Rattanawong, Sikarin Upala, Tanawan Riangwiwat, Veeravich Jaruvongvanich, Anawin Sanguankeo, Wasawat Vutthikraivit, Eugene H Chung

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 7 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 7 syntheses or guidelines pooled it, 73 citations in OpenAlex.

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  5. Prognostic impact of atrial fibrillation in hypertrophic cardiomyopathy: a systematic review.Clinical research in cardiology : official journal of the German Cardiac Society · 2021
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  7. Atrial fibrillation and risk of major arrhythmic events in Brugada syndrome: A meta-analysis.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2019
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Pattara RattanawongUniversity of Hawaii Internal Medicine Residency Program, Honolulu, HI, USA.
Sikarin UpalaSection of Endocrinology, Diabetes, and Metabolism, Department of Medicine, University of Chicago, Chicago, IL, USA. sikarinu@gmail.com.ORCID http://orcid.org/0000-0002-6047-5302
Tanawan RiangwiwatUniversity of Hawaii Internal Medicine Residency Program, Honolulu, HI, USA.
Veeravich JaruvongvanichUniversity of Hawaii Internal Medicine Residency Program, Honolulu, HI, USA.
Anawin SanguankeoDepartment of Preventive and Social Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.
Wasawat VutthikraivitFaculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.
Eugene H ChungDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
University of Hawaii System · USSiriraj Hospital · THTexas Tech University · USUniversity of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeRecent studies suggest that atrial fibrillation (AF) is associated with increased cardiovascular risk and mortality including sudden cardiac death (SCD). According to the Cardiovascular Heath Study cohort, the incident rate of SCD was higher in the AF population (2.9 per 1000 per year) compared with non-AF controls (1.3 per 1000 per year). In this study, we performed a systematic review and meta-analysis to explore the association between AF and SCD.

methodsWe comprehensively searched the databases of MEDLINE and EMBASE from inception to January 2017. Included studies were published prospective or retrospective cohort studies that compared the risk of developing SCD, defined by World Health Organization's criteria, in AF patients versus non-AF patients. Data from each study were combined using the random-effects, generic inverse variance method of DerSimonian and Laird to calculate the risk ratios and 95% confidence intervals.

resultsTwenty-seven studies from January 1991 to February 2017 involving 8401 AF patients and 67,608 non-AF controls were included in this meta-analysis. Compared with controls, AF patients had a significantly higher risk of SCD in overall analysis (pooled risk ratio = 2.04, 95% confidence interval: 1.77-2.35, p < 0.01, I

conclusionsOur meta-analysis demonstrates a statistically significant increased risk of SCD with AF in the general population and in those with previous myocardial infarction, coronary artery disease, heart failure, HCM, Brugada syndrome, and an implanted rhythm device.

Indexed as

Cause of DeathAtrial FibrillationCatheter AblationComorbidityDeath, Sudden, CardiacDefibrillators, ImplantableFemaleHeart FailureHumansIncidenceMaleMyocardial InfarctionRisk AssessmentSurvival AnalysisAtrial fibrillationSudden cardiac death

Identifiers

PMID29332241
OpenAlexW2782932650

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.