Evidence map›Paper›PMID 29331674›Full record

ArticleEBioMedicine2018

HIV Activates the Tyrosine Kinase Hck to Secrete ADAM Protease-Containing Extracellular Vesicles.

J-H Lee, C Ostalecki, Z Zhao, T Kesti, H Bruns, B Simon, T Harrer, K Saksela, A S Baur

Open access · goldAbstract read
In one paragraph

Article in EBioMedicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 33 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Extracellular Vesicles and Their Use as Vehicles of Immunogens.Methods in molecular biology (Clifton, N.J.) · 2022
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

J-H LeeDepartment of Dermatology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Hartmannstr. 14, 91054 Erlangen, Germany.
C OstaleckiDepartment of Dermatology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Hartmannstr. 14, 91054 Erlangen, Germany.
Z ZhaoDepartment of Virology, University of Helsinki, PO Box 21, Haartmaninkatu 3, 00014, Finland.
T KestiDepartment of Virology, University of Helsinki, PO Box 21, Haartmaninkatu 3, 00014, Finland.
H BrunsDepartment of Internal Medicine V, Haematology and Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Hartmannstr. 14, 91054 Erlangen, Germany.
B SimonDepartment of Dermatology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Hartmannstr. 14, 91054 Erlangen, Germany.
T HarrerDepartment for Internal Medicine 3, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Ulmenweg 18, Erlangen, Germany.
K SakselaDepartment of Virology, University of Helsinki, PO Box 21, Haartmaninkatu 3, 00014, Finland.
A S BaurDepartment of Dermatology, Universitätsklinikum Erlangen, Friedrich-Alexander Universität Erlangen-Nürnberg, Hartmannstr. 14, 91054 Erlangen, Germany. Electronic address: andreas.baur@uk-erlangen.de.
Friedrich-Alexander-Universität Erlangen-Nürnberg · DEUniversity of Helsinki · FIUniversitätsklinikum Erlangen · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ADAM17 ProteinCase-Control StudiesCell LineExtracellular VesiclesHepatocytesHIV Core Protein p24HIV InfectionsHost-Pathogen InteractionsHumansLiverMaleMyeloid Cellsnef Gene Products, Human Immunodeficiency VirusProto-Oncogene Proteins c-hckADAM17 ProteinADAM17 protein, humanHCK protein, humanHIV Core Protein p24nef Gene Products, Human Immunodeficiency VirusProto-Oncogene Proteins c-hckADAM17Chronic HIV infectionHckHepatocytesLiverMyeloid cellsNefPlasma extracellular vesicles

Identifiers

PMID29331674
PMCPMC5836510
OpenAlexW2781556955

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.