Evidence map›Paper›PMID 29331046›Full record

ArticleAllergy2018

Prevalence, severity, and risk factors for acute exacerbations of nasal and sinus symptoms by chronic rhinosinusitis status.

J R Kuiper, A G Hirsch, K Bandeen-Roche, A S Sundaresan, B K Tan, R P Schleimer, R C Kern, W F Stewart, B S Schwartz

Abstract read
In one paragraph

Article in Allergy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Definition and characteristics of acute exacerbation in adult patients with chronic rhinosinusitis: a systematic review.Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale · 2020
    Pooled it
  3. Acute Exacerbations of Chronic Rhinosinusitis.Current allergy and asthma reports · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The Role of Viruses in the Inception of Chronic Rhinosinusitis.Clinical and experimental otorhinolaryngology · 2022
    Review
  12. Review
  13. Article
  14. Review
  15. Clinical factors associated with acute exacerbations of chronic rhinosinusitis.The Journal of allergy and clinical immunology · 2020
    Article
  16. Article
  17. Seasonal variations in chronic rhinosinusitis symptom burden may be explained by changes in mood.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2019
    Article
  18. Workplace Indirect Cost Impacts of Nasal and Sinus Symptoms and Related Conditions.Journal of occupational and environmental medicine · 2019
    Article
  19. Clinical predictors of cystic fibrosis chronic rhinosinusitis severity.International forum of allergy & rhinology · 2019
    Observational
  20. Current Understanding of the Acute Exacerbation of Chronic Rhinosinusitis.Frontiers in cellular and infection microbiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

J R KuiperDepartment of Environmental Health and Engineering, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MA, USA.ORCID 0000-0002-4285-1562
A G HirschDepartment of Epidemiology and Health Services Research, Geisinger, Danville, PA, USA.
K Bandeen-RocheDepartment of Biostatistics, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
A S SundaresanDepartment of Epidemiology and Health Services Research, Geisinger, Danville, PA, USA.
B K TanDepartment of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
R P SchleimerDepartment of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
R C KernDepartment of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.
W F StewartResearch Development and Dissemination, Sutter Health, San Francisco, CA, USA.
B S SchwartzDepartment of Environmental Health and Engineering, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MA, USA.ORCID 0000-0002-0739-9865

Funding

Targeted Research Training CoreT42OH008428 · OH · JOHNS HOPKINS UNIVERSITY · PI RAMACHANDRAN, GURUMURTHY · 2005 to 2025
$31.1M
Systems Genetics Approach to Gene Discovery in Chronic RhinosinusitisU19AI106683 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2014 to 2017
$7.9M
Initiators, biomarkers and mechanisms of epithelial dysfunction and immune pathogenesis in chronic rhinosinusitis and aspirin exacerbated respiratory disease (AERD)R01AI137174 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2018 to 2022
$3.1M
Systems Genetics Approach to Gene Discovery in Chronic RhinosinusitisP01AI106683 · NIAID · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SCHLEIMER, ROBERT P · 2013 to 2013
$1.7M
ACL HHS T42OH008428NIAID NIH HHS P01 AI106683NIAID NIH HHS R01 AI137174NIAID NIH HHS U19 AI106683NIOSH CDC HHS T42 OH008428
6 · The paper itself

Abstract

backgroundNasal and sinus symptoms (NSS) are common to many health conditions, including chronic rhinosinusitis (CRS). Few studies have investigated the occurrence and severity of, and risk factors for, acute exacerbations of NSS (AENSS) by CRS status (current, past, or never met European Position Paper on Rhinosinusitis [EPOS] criteria for CRS).

methodsFour seasonal questionnaires were mailed to a stratified random sample of Geisinger primary care patients. Logistic regression was used to identify individual characteristics associated with AENSS occurrence and severity by CRS status (current long-term, current recent, past, never) using EPOS subjective symptoms-only (EPOS

resultsBaseline and at least 1 follow-up questionnaires were available from 4736 subjects. Self-reported NSS severity with exacerbation was worst in the current long-term CRS group. AENSS was common in all subgroups examined and generally more common among those with current EPOS

conclusionsIn this first longitudinal, population-based study of 3 AENSS definitions, NSS and AENSS were both common, sometimes severe, and differed by EPOS

Indexed as

Chronic DiseaseDisease ProgressionFemaleHumansLongitudinal StudiesMalePopulation SurveillancePrevalenceRhinitisRisk FactorsSeverity of Illness IndexSinusitisSurveys and QuestionnairesSymptom Assessmentchronic rhinosinusitisepidemiologyexacerbationlongitudinal

Identifiers

PMID29331046
PMCPMC5993580

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.