ArticleSleep & breathing = Schlaf & Atmung2018
Comorbid insomnia and sleep apnea in Veterans with post-traumatic stress disorder.
Article in Sleep & breathing = Schlaf & Atmung, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 38 citations in OpenAlex.
- Cognitive Behavioral Therapy Alone or in Combination with Eszopiclone in Comorbid Insomnia and Obstructive Sleep Apnea in Veterans with Posttraumatic Stress Disorder: A Randomized Trial.The Psychiatric quarterly · 2025Trial
- Comorbid Insomnia and Sleep Apnea Mechanistic Convergence, Phenotypic Heterogeneity, and Clinical Implications.Current sleep medicine reports · 2026Article
- The ventilatory response to arousal from sleep is elevated in young individuals with post-traumatic stress disorder symptoms.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026Article
- Prevalence of comorbid Insomnia and sleep apnoea (COMISA) in patients with obesity hypoventilation syndrome.Sleep & breathing = Schlaf & Atmung · 2026Article
- Determinants of treatment response to cognitive behavioral therapy in veterans presenting with comorbid insomnia and sleep apnea.Sleep & breathing = Schlaf & Atmung · 2025Article
- Residual sleepiness in veterans with post-traumatic stress disorder and obstructive sleep apnea.Sleep & breathing = Schlaf & Atmung · 2023Article
- A Narrative Review of the Association between Post-Traumatic Stress Disorder and Obstructive Sleep Apnea.Journal of clinical medicine · 2022Review
- The Many Faces of Sleep Disorders in Post-Traumatic Stress Disorder: An Update on Clinical Features and Treatment.Neuropsychobiology · 2022Review
- Impact of low arousal threshold on treatment of obstructive sleep apnea in patients with post-traumatic stress disorder.Sleep & breathing = Schlaf & Atmung · 2021Article
- Sleep in PTSD: treatment approaches and outcomes.Current opinion in psychology · 2020Review
- Sleep Disturbances and Suicidality in Posttraumatic Stress Disorder: An Overview of the Literature.Frontiers in psychiatry · 2020Review
- Co-Morbid Insomnia and Sleep Apnea (COMISA): Prevalence, Consequences, Methodological Considerations, and Recent Randomized Controlled Trials.Brain sciences · 2019Review
- Changes in insomnia severity with advanced PAP therapy in patients with posttraumatic stress symptoms and comorbid sleep apnea: a retrospective, nonrandomized controlled study.Military Medical Research · 2019Article
- Review
- Recent Advancements in Treating Sleep Disorders in Co-Occurring PTSD.Current psychiatry reports · 2018Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe purpose of this study was to determine the impact of insomnia in Veterans with post-traumatic stress disorder (PTSD) and obstructive sleep apnea (OSA) on health-related outcomes before and after 12 weeks of continuous positive airway pressure (CPAP) treatment.
methodsWe conducted a prospective cohort study of Veterans with PTSD and documented apnea hypopnea index (AHI) ≥ 5 with and without clinically significant insomnia as determined by the Insomnia Severity Index (ISI). Health-related outcomes including PTSD checklist (PCL-M), SF-36, and Pittsburgh Sleep Quality Index (PSQI) were assessed at baseline and 12 weeks after initiation of OSA treatment. CPAP adherence was retrieved at each visit.
resultsSeventy-two Veterans including 36 with comorbid insomnia and OSA (COMISA) and 36 OSA-only were enrolled. Veterans with COMISA were younger (p = 0.03), had lower BMI (p < 0.001), and were more likely to report depression than those with OSA-only (p = 0.004). Although AHI was higher in the COMISA (p = 0.01), both groups expressed comparable daytime sleepiness (p = 0.16). The COMISA group had no significant change in SF-36 and PSQI after 12 weeks of treatment and used CPAP much less frequently than OSA-only group (p = 0.001).
conclusionsCOMISA in Veterans with PTSD is associated with worse quality of life than those with OSA-only. Insomnia should be assessed in Veterans with PTSD who are not adherent to CPAP treatment.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.