Evidence map›Paper›PMID 29330761›Full record

ArticleJournal of pharmacokinetics and pharmacodynamics2018

Correction to: Scientific white paper on concentration-QTc modeling.

Christine Garnett, Peter L Bonate, Qianyu Dang, Georg Ferber, Dalong Huang, Jiang Liu, Devan Mehrotra, Steve Riley, Philip Sager, Christoffer Tornoe and 1 more

Abstract readPublished Erratum
PubMed Publisher
In one paragraph

Article in Journal of pharmacokinetics and pharmacodynamics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Estimation of QT interval prolongation through model-averaging.Journal of pharmacokinetics and pharmacodynamics · 2017
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Christine GarnettDivision of Cardiovascular and Renal Products, Office of New Drugs, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA. christine.garnett@fda.hhs.gov.ORCID 0000-0002-4108-2511
Peter L BonateAstellas Pharma Global Development, Northbrook, IL, USA.
Qianyu DangOffice of Biostatistics, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.
Georg FerberStatistik Georg Ferber GmbH, Riehen, Switzerland.
Dalong HuangOffice of Biostatistics, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.
Jiang LiuDivision of Pharmacometrics, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.
Devan MehrotraBiostatistics, Merck & Co., Inc., Gwynedd, PA, USA.
Steve RileyClinical Pharmacology, Pfizer Inc., New York, NY, USA.
Philip SagerStanford University, Stanford, CA, USA.
Christoffer TornoeClinical Reporting, Novo Nordisk A/S, Bagsværd, Denmark.
Yaning WangDivision of Pharmacometrics, Office of Clinical Pharmacology, Office of Translational Sciences, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The original version of this article unfortunately contained an error in Equation 1 under the section "Pre-specified linear mixed effects model". The correct equation has given below.

Identifiers

PMID29330761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.