ReviewInfection2018
Advances in serological, imaging techniques and molecular diagnosis of Toxoplasma gondii infection.
Review in Infection, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 55 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
55 citing papers in PubMed, 2 syntheses or guidelines pooled it, 118 citations in OpenAlex.
- Prevalence ofFrontiers in veterinary science · 2021Pooled it
- Acute Toxoplasma infection in pregnant women worldwide: A systematic review and meta-analysis.PLoS neglected tropical diseases · 2019Pooled it
- Seroepidemiology of Toxoplasma gondii infection in people with alcohol consumption in Durango, Mexico.PloS one · 2021Trial
- Immediate versus deferred antiretroviral therapy in HIV-infected patients presenting with acute AIDS-defining events (toxoplasmosis, Pneumocystis jirovecii-pneumonia): a prospective, randomized, open-label multicenter study (IDEAL-study).AIDS research and therapy · 2019Trial
- Outbreak of toxoplasmosis with pulmonary involvement in immunocompetent military populationBiomedica : revista del Instituto Nacional de Salud · 2026Article
- Innovations, Applications, and Future Trends in Veterinary Diagnostic Technologies.Transboundary and emerging diseases · 2026Review
- Acute Respiratory Failure due to Pulmonary Toxoplasmosis in an Immunocompetent Patient: A Case Report.Case reports in critical care · 2026Article
- Evolution ofJournal of parasitology research · 2026Review
- Characterization of Excretory-Secretory Antigens of Toxoplasma gondii in the Acute and Chronic Phase of Toxoplasmosis in a Murine Model.Acta parasitologica · 2025Article
- Comprehensive diagnostic approaches to feline toxoplasmosis: Bridging traditional methods and emerging technologies.Virulence · 2025Review
- Investigation of the Prevalence of Toxoplasma gondii in Meat, Meat Organs, Milk, Dairy Products and Eggs in Different Animals, in Iran.Veterinary medicine and science · 2025Review
- Detection of toxoplasmosis by serology and nested-PCR in kidney transplant recipients and patients on hemodialysis from Sri Lanka.BMC infectious diseases · 2025Article
- Development of an Immunochromatographic Test with Recombinant MIC2-MIC3 Fusion Protein for Serological Detection ofVeterinary sciences · 2025Article
- IgM Antibody Detection as a Diagnostic Marker for Acute Toxoplasmosis: Current Status of Studies and Main Limitations.Antibodies (Basel, Switzerland) · 2025Review
- Serological and molecular detection of Toxoplasma Gondii among cancer patients in Sohag, Upper Egypt: a case-control study.Scientific reports · 2025Article
- The Potential Role of Toxoplasma gondii Infection in Multiple Sclerosis Development: A Seroepidemiological Study in North Khorasan Province, Iran.Acta parasitologica · 2025Article
- HIV-Related Toxoplasmosis Infection. A Rare Case of Simultaneous Cardiac and Cerebral Involvement.International medical case reports journal · 2025Article
- Seroprevalence ofAnimals : an open access journal from MDPI · 2024Article
- Development of an indirect ELISA for detecting Toxoplasma gondii IgG antibodies based on a recombinant TgIMP1 protein.PLoS neglected tropical diseases · 2024Article
- Development of a LAMP method with lateral flow DNA chromatography to diagnose toxoplasmosis in immunocompromised patients.Tropical medicine and health · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundToxoplasmosis is worldwide distributed zoonotic infection disease with medical importance in immunocompromised patients, pregnant women and congenitally infected newborns. Having basic information on the traditional and new developed methods is essential for general physicians and infectious disease specialists for choosing a suitable diagnostic approach for rapid and accurate diagnosis of the disease and, consequently, timely and effective treatment.
methodsWe conducted English literature searches in PubMed from 1989 to 2016 using relevant keywords and summarized the recent advances in diagnosis of toxoplasmosis.
resultsEnzyme-linked immunosorbent assay (ELISA) was most used method in past century. Recently advanced ELISA-based methods including chemiluminescence assays (CLIA), enzyme-linked fluorescence assay (ELFA), immunochromatographic test (ICT), serum IgG avidity test and immunosorbent agglutination assays (ISAGA) have shown high sensitivity and specificity. Recent studies using recombinant or chimeric antigens and multiepitope peptides method demonstrated very promising results to development of new strategies capable of discriminating recently acquired infections from chronic infection. Real-time PCR and loop-mediated isothermal amplification (LAMP) are two recently developed PCR-based methods with high sensitivity and specificity and could be useful to early diagnosis of infection. Computed tomography, magnetic resonance imaging, nuclear imaging and ultrasonography could be useful, although their results might be not specific alone.
conclusionThis review provides a summary of recent developed methods and also attempts to improve their sensitivity for diagnosis of toxoplasmosis. Serology, molecular and imaging technologies each has their own advantages and limitations which can certainly achieve definitive diagnosis of toxoplasmosis by combining these diagnostic techniques.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.