SynthesisClinical oral investigations2018
Effectiveness for dentin hypersensitivity treatment of non-carious cervical lesions: a meta-analysis.
Synthesis in Clinical oral investigations, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
32 citing papers in PubMed, 2 syntheses or guidelines pooled it, 93 citations in OpenAlex.
- The Decision Tree for Clinical Management of Dentin Hypersensitivity. A Consensus Report.Oral health & preventive dentistry · 2022Pooled it
- Clinical performance of bulk-fill and conventional resin composite restorations in posterior teeth: a systematic review and meta-analysis.Clinical oral investigations · 2019Pooled it
- Randomized clinical trial evaluating kinetic benefits of desensitizing agents: Magnitude, onset, and stability of relief.Journal of periodontology · 2025Trial
- Clinical evaluation of the effect of 980 nm diode laser and fluoride varnish on dentin hypersensitivity.Brazilian oral research · 2025Trial
- Assessment of the Oral Health Impact Profile (OHIP-14) improvement of different treatments for dentin hypersensitivity in noncarious cervical lesions-a randomized clinical study.Clinical oral investigations · 2022Trial
- Combination of two desensitizing protocols to control dentin hypersensitivity in non-carious lesions: a randomized, double-blind clinical trial.Clinical oral investigations · 2022Trial
- Low level laser therapy, Er,Cr:YSGG laser and fluoride varnish for treatment of dentin hypersensitivity after periodontal surgery: A randomized clinical trial.Lasers in medical science · 2021Trial
- Low-power laser and potassium oxalate gel in the treatment of cervical dentin hypersensitivity-a randomized clinical trial.Clinical oral investigations · 2020Trial
- 38% silver diamine fluoride for dentine hypersensitivity treatment: anFrontiers in oral health · 2026Article
- The Impact of Calcination on the Structure, Bioactivity, and Biocompatibility of Sol-Gel-Derived Glasses.ACS omega · 2025Article
- Article
- Evaluation of Dentin Tubule Occlusion Using Diode Laser and Shield Force Plus: A Comparative Study.Journal of lasers in medical sciences · 2025Article
- Comparison of casein phosphopeptide-amorphous calcium phosphate fluoride paste and a propolis-containing herbal toothpaste in dentinal hypersensitivity: A randomized trial.Dental research journal · 2025Article
- Clinical Investigation of Bioelectric Toothbrush for Dentin Hypersensitivity Management: A Randomized Double-Blind Study.Bioengineering (Basel, Switzerland) · 2024Article
- Analysis of dentin wear and biological properties promoted by experimental inoffice desensitizing materials.BMC oral health · 2024Article
- Article
- Stereomicroscopic Aspects of Non-Carious Cervical Lesions.Diagnostics (Basel, Switzerland) · 2023Article
- The Effectiveness of Calcium Phosphates in the Treatment of Dentinal Hypersensitivity: A Systematic Review.Bioengineering (Basel, Switzerland) · 2023Review
- Photobiomodulation Therapy and Pulp-Regenerative Endodontics: A Narrative Review.Bioengineering (Basel, Switzerland) · 2023Review
- Clinical Evidence of Biomimetic Hydroxyapatite in Oral Care Products for Reducing Dentin Hypersensitivity: An Updated Systematic Review and Meta-Analysis.Biomimetics (Basel, Switzerland) · 2023Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this review is to conduct a systematic review and meta-analysis comparing the effectiveness of in-home or in-office treatments for dentin hypersensitivity. MATERIALS AND
methodsAn electronic search without restriction on dates or languages was performed in four electronic databases until March 2017. In addition, hand-searches in regular journals and in the gray literature were also conducted. To develop the search strategy, clinical questions were formulated using the PICOS method. Eligibility criteria included randomized clinical trials (RCTs) that compared the effectiveness of different agents for the treatment of dentin hypersensitivity through chemical occlusion, physical occlusion, nerve desensitization, or photobiomodulation (low-level light therapy). This systematic review was registered in PROSPERO under number CRD42016039394.
resultsTwenty-five RCTs (16 parallel; 9 split-mouth), published from 1992 to 2016, were included. The results of the meta-analysis showed that in-office subgroups treated with chemical or physical occlusion of dentin tubules and nerve desensitization had a statistically significant difference from placebo, with P < 0.00001, P < 0.00001, and P = 0.02, respectively. For in-home treatments, the results of the meta-analysis showed that only those subgroups treated with chemical occlusion of dentin tubules and nerve desensitization exhibited a statistically significant difference from placebo, with P < 0.00001 and P = 0.03, respectively.
conclusionsThe results of pairwise meta-analysis suggest that among in-office treatments, dentinal tubule occlusion (whether chemical or physical) and nerve desensitization provide the best outcomes for treatment of dentin hypersensitivity. For in-home treatments, only chemical occlusion of dentin tubules and nerve desensitization showed a greater treatment efficacy than placebo and the difference was statistically significant.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.