Evidence map›Paper›PMID 29330525›Full record

ArticleScientific reports2018

Distinct modulation of inactivation by a residue in the pore domain of voltage-gated Na

Rene Cervenka, Peter Lukacs, Vaibhavkumar S Gawali, Song Ke, Xaver Koenig, Lena Rubi, Touran Zarrabi, Karlheinz Hilber, Walter Sandtner, Anna Stary-Weinzinger and 1 more

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Rene CervenkaCenter for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
Peter LukacsCenter for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
Vaibhavkumar S GawaliCenter for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
Song KeDepartment of Pharmacology and Toxicology, University of Vienna, Althanstrasse 14, UZA 2, A-1090, Vienna, Austria.
Xaver KoenigCenter for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
Lena RubiCenter for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
Touran ZarrabiCenter for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
Karlheinz HilberCenter for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
Walter SandtnerCenter for Physiology and Pharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria.
Anna Stary-WeinzingerDepartment of Pharmacology and Toxicology, University of Vienna, Althanstrasse 14, UZA 2, A-1090, Vienna, Austria.ORCID http://orcid.org/0000-0002-9202-0484
Hannes TodtCenter for Physiology and Pharmacology, Department of Neurophysiology and Neuropharmacology, Medical University of Vienna, Waehringerstrasse 13a, 1090, Vienna, Austria. hannes.todt@meduniwien.ac.at.ORCID http://orcid.org/0000-0002-1147-4370
Medical University of Vienna · ATUniversity of Vienna · AT

Funding

Austrian Science Fund FWF W 1232
6 · The paper itself

Abstract

Inactivation of voltage-gated Na

Indexed as

MutationAnimalsCysteineEnzyme ActivationModels, MolecularMolecular Dynamics SimulationMuscle ProteinsProtein Structure, TertiaryRatsSodium ChannelsXenopus laevisCysteineMuscle ProteinsScn4a protein, ratSodium Channels

Identifiers

PMID29330525
PMCPMC5766632
OpenAlexW2784164757

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.