Evidence map›Paper›PMID 29330448›Full record

Trial reportScientific reports2018

Visual field loss and vision-related quality of life in the Italian Primary Open Angle Glaucoma Study.

Eliana Rulli, Luciano Quaranta, Ivano Riva, Davide Poli, Lital Hollander, Fabio Galli, Andreas Katsanos, Francesco Oddone, Valter Torri, Robert N Weinreb and 1 more

Erratum issuedAbstract readClinical Trial
In one paragraph

Trial report in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 31 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The first step in developing an International Classification of Functioning, Disability and Health Core Set for Vision Loss: A systematic review.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2024
    Pooled it
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  3. Development of the International Classification of Functioning, Disability and Health Core Set for Vision Loss: Insights From the Lived Experience of People With Vision Loss.Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) · 2026
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  14. Applications and Current Medico-Legal Challenges of Telemedicine in Ophthalmology.International journal of environmental research and public health · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Eliana RulliIRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.ORCID http://orcid.org/0000-0003-1058-4137
Luciano QuarantaDMSS, University of Brescia, Brescia, Italy. luciano.quaranta@unibs.it.
Ivano RivaIRCCS - Fondazione GB Bietti per lo Studio e la Ricerca in Oftalmologia, Rome, Italy.
Davide PoliIRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
Lital HollanderIRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
Fabio GalliIRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
Andreas KatsanosDMSS, University of Brescia, Brescia, Italy.
Francesco OddoneIRCCS - Fondazione GB Bietti per lo Studio e la Ricerca in Oftalmologia, Rome, Italy.
Valter TorriIRCCS - Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy.
Robert N WeinrebHamilton Glaucoma Center, Shiley Eye Institute, and the Department of Ophthalmology, University of California, San Diego, CA, USA.
Italian Study Group on QoL in Glaucoma

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to examine the relationship between visual field (VF) loss, vision-related quality of life (QoL) and glaucoma-related symptoms in a large cohort of primary open angle glaucoma (POAG) patients. POAG patients with or without VF defects or "glaucoma suspect" patients were considered eligible. QoL was assessed using the validated versions of the 25-item National Eye Institute Visual Function Questionnaire (NEI-VFQ-25) and glaucoma-related symptoms were assessed using the Glaucoma Symptom Scale (GSS). Patients were classified as having VF damage in one eye (VFD-1), both eyes (VFD-2), or neither eye (VFD-0). 3227 patients were enrolled and 2940 were eligible for the analysis. 13.4% of patients were classified in the VFD-0, 23.7% in the VFD-1, and 62.9% in the VFD-2 group. GSS visual symptoms domain (Func-4) and GSS non-visual symptoms domain (Symp-6) scores were similar for the VFD-0 and VFD-1 groups (p = 0.133 and p = 0.834 for Func-4 and Symp-6, respectively). VFD-0 group had higher scores than VFD-2 both in Func-4 (p < 0.001) and Symp-6 domains (p = 0.035). Regarding the NEI-VFQ-25, our data demonstrated that bilateral VF defects are associated with vision-related QoL deterioration, irrespective of visual acuity.

Indexed as

AdultAgedAged, 80 and overFemaleGlaucoma, Open-AngleHumansItalyMaleMiddle AgedQuality of LifeSurveys and QuestionnairesVision DisordersVisual Field TestsYoung Adult

Identifiers

PMID29330448
PMCPMC5766542

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.