Evidence map›Paper›PMID 29330436›Full record

ArticleScientific reports2018

Blood transcriptomics of captive forest musk deer (Moschus berezovskii) and possible associations with the immune response to abscesses.

Xiaoning Sun, Ruibo Cai, Xuelin Jin, Aaron B A Shafer, Xiaolong Hu, Shuang Yang, Yimeng Li, Lei Qi, Shuqiang Liu, Defu Hu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Xiaoning SunLaboratory of Non-invasive Research Technology for Endangered Species, College of Nature Conservation,Beijing Forestry University, No. 35 Tsinghua East Road, Haidian District, Beijing, 100083, China.
Ruibo CaiLaboratory of Non-invasive Research Technology for Endangered Species, College of Nature Conservation,Beijing Forestry University, No. 35 Tsinghua East Road, Haidian District, Beijing, 100083, China.
Xuelin JinShaanxi Institute of Zoology, No. 88 Xing Qing Ave Xian, Shaanxi, 710032, China.
Aaron B A ShaferForensic Science and Environmental & Life Sciences, Trent University,1600 West Bank Drive,Peterborough, Ontario, Canada.
Xiaolong HuLaboratory of Non-invasive Research Technology for Endangered Species, College of Nature Conservation,Beijing Forestry University, No. 35 Tsinghua East Road, Haidian District, Beijing, 100083, China.
Shuang YangLaboratory of Non-invasive Research Technology for Endangered Species, College of Nature Conservation,Beijing Forestry University, No. 35 Tsinghua East Road, Haidian District, Beijing, 100083, China.
Yimeng LiLaboratory of Non-invasive Research Technology for Endangered Species, College of Nature Conservation,Beijing Forestry University, No. 35 Tsinghua East Road, Haidian District, Beijing, 100083, China.
Lei QiLaboratory of Non-invasive Research Technology for Endangered Species, College of Nature Conservation,Beijing Forestry University, No. 35 Tsinghua East Road, Haidian District, Beijing, 100083, China.
Shuqiang LiuLaboratory of Non-invasive Research Technology for Endangered Species, College of Nature Conservation,Beijing Forestry University, No. 35 Tsinghua East Road, Haidian District, Beijing, 100083, China. liushuqiang@bjfu.edu.cn.
Defu HuLaboratory of Non-invasive Research Technology for Endangered Species, College of Nature Conservation,Beijing Forestry University, No. 35 Tsinghua East Road, Haidian District, Beijing, 100083, China. hudf@bjfu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Forest musk deer (Moschus berezovskii; FMD) are both economically valuable and highly endangered. A problem for FMD captive breeding programs has been the susceptibility of FMD to abscesses. To investigate the mechanisms of abscess development in FMD, the blood transcriptomes of three purulent and three healthy individuals were generated. A total of ~39.68 Gb bases were generated using Illumina HiSeq 4000 sequencing technology and 77,752 unigenes were identified after assembling. All the unigenes were annotated, with 63,531 (81.71%) mapping to at least one database. Based on these functional annotations, 45,798 coding sequences (CDS) were detected, along with 12,697 simple sequence repeats (SSRs) and 65,536 single nucleotide polymorphisms (SNPs). A total of 113 unigenes were found to be differentially expressed between healthy and purulent individuals. Functional annotation indicated that most of these differentially expressed genes were involved in the regulation of immune system processes, particularly those associated with parasitic and bacterial infection pathways.

Indexed as

Gene Regulatory NetworksAbscessAnimalsDeerGene Expression ProfilingGene Expression RegulationHigh-Throughput Nucleotide SequencingMicrosatellite RepeatsMolecular Sequence AnnotationPolymorphism, Single NucleotideSequence Analysis, RNA

Identifiers

PMID29330436
PMCPMC5766596

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.