Evidence map›Paper›PMID 29330415›Full record

ArticleNature communications2018

Unusual multiscale mechanics of biomimetic nanoparticle hydrogels.

Yunlong Zhou, Pablo F Damasceno, Bagganahalli S Somashekar, Michael Engel, Falin Tian, Jian Zhu, Rui Huang, Kyle Johnson, Carl McIntyre, Kai Sun and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Smart Materials Design for Antibacterial Application.Pharmaceutical nanotechnology · 2025
    Review
  4. Article
  5. Article
  6. Hybrid Vesicles Enable Mechano-Responsive Hydrogel Degradation.Angewandte Chemie (International ed. in English) · 2023
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Re-designing materials for biomedical applications: from biomimicry to nature-inspired chemical engineering.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2019
    Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yunlong ZhouSchool of Biomedical Engineering, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, 325011, China. zhouyl@wibe.ac.cn.ORCID http://orcid.org/0000-0001-5654-1170
Pablo F DamascenoDepartment of Chemical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Bagganahalli S SomashekarBiophysics and Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.
Michael EngelDepartment of Chemical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Falin TianSchool of Biomedical Engineering, School of Ophthalmology and Optometry and Eye Hospital, Wenzhou Medical University, Wenzhou, Zhejiang, 325011, China.
Jian ZhuDepartment of Chemical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Rui HuangBiophysics and Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.
Kyle JohnsonDepartment of Materials Science and Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Carl McIntyreDepartment of Materials Science and Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Kai SunDepartment of Materials Science and Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Ming YangDepartment of Chemical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Peter F GreenDepartment of Materials Science and Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Ayyalusamy RamamoorthyBiophysics and Department of Chemistry, University of Michigan, Ann Arbor, MI, 48109, USA.
Sharon C GlotzerDepartment of Chemical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA.
Nicholas A KotovDepartment of Chemical Engineering, University of Michigan, Ann Arbor, MI, 48109, USA. kotov@umich.edu.ORCID http://orcid.org/0000-0002-6864-5804

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viscoelastic properties are central for gels and other materials. Simultaneously, high storage and loss moduli are difficult to attain due to their contrarian requirements to chemical structure. Biomimetic inorganic nanoparticles offer a promising toolbox for multiscale engineering of gel mechanics, but a conceptual framework for their molecular, nanoscale, mesoscale, and microscale engineering as viscoelastic materials is absent. Here we show nanoparticle gels with simultaneously high storage and loss moduli from CdTe nanoparticles. Viscoelastic figure of merit reaches 1.83 MPa exceeding that of comparable gels by 100-1000 times for glutathione-stabilized nanoparticles. The gels made from the smallest nanoparticles display the highest stiffness, which was attributed to the drastic change of GSH configurations when nanoparticles decrease in size. A computational model accounting for the difference in nanoparticle interactions for variable GSH configurations describes the unusual trends of nanoparticle gel viscoelasticity. These observations are generalizable to other NP gels interconnected by supramolecular interactions and lead to materials with high-load bearing abilities and energy dissipation needed for multiple technologies.

Indexed as

Biomimetic MaterialsCadmium CompoundsGlutathioneHydrogelsMechanical PhenomenaNanoparticlesTelluriumViscoelastic SubstancesCadmium Compoundscadmium tellurideGlutathioneHydrogelsTelluriumViscoelastic Substances

Identifiers

PMID29330415
PMCPMC5766503

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.