ReviewEndocrine connections2018
Diagnosis, management, histology and genetics of sporadic primary hyperparathyroidism: old knowledge with new tricks.
Review in Endocrine connections, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 40 citations in OpenAlex.
- Immunohistochemical Expression of CaSR, VDR, and AMA in Parathyroid Tumors in Relation to Hypercalcemia Severity in Primary Hyperparathyroidism.Current issues in molecular biology · 2026Article
- Association Between Biochemical Parameters, Parathyroid Gland Morphometry, and Dual-Phase MIBI SPECT/CT Findings in Primary Hyperparathyroidism.Journal of clinical medicine · 2026Article
- A Giant Parathyroid Adenoma Presenting as Coughs and Dyspnea in a Young Woman: A Case Report.Clinical case reports · 2026Article
- Design of Nanostructured Enzyme Immobilized Platforms for Precise Diagnosis and Treatment of Endocrine Disease: An Updated Review.International journal of nanomedicine · 2026Review
- Vitamin D receptor: a possible biomarker for sporadic parathyroid adenoma?Updates in surgery · 2025Article
- A Pilot Study ofBalkan journal of medical genetics : BJMG · 2024Article
- Atypically presented dysphagia in a patient with primary hyperparathyroidism that resolved after parathyroidectomy: A case report.International journal of surgery case reports · 2024Article
- Hyperparathyroidism: Pathological Diagnosis and Association with Parathyroid Localization.Materia socio-medica · 2023Article
- Sporadic parathyroid adenoma: an updated review of molecular genetics.Frontiers in endocrinology · 2023Review
- Immunohistochemical Profile of Parathyroid Tumours: A Comprehensive Review.International journal of molecular sciences · 2022Review
- Safe provision of elective endocrine surgery operations amid the COVID-19 crisis.Annals of the Royal College of Surgeons of England · 2022Article
- Molecular Mechanisms of Parathyroid Disorders in Chronic Kidney Disease.Metabolites · 2022Review
- A Functional Network Model of the Metastasis Suppressor PEBP1/RKIP and Its Regulators in Breast Cancer Cells.Cancers · 2021Article
- Analyzing Genetic Differences Between Sporadic Primary and Secondary/Tertiary Hyperparathyroidism by Targeted Next-Generation Panel Sequencing.Endocrine pathology · 2021Article
- Attitude of the surgical approach in hyperparathyroidism: A retrospective study.Experimental and therapeutic medicine · 2021Article
- Shear Wave Elastography in Patients with Primary and Secondary Hyperparathyroidism.Journal of clinical medicine · 2021Article
- A case of Turner's syndrome with Graves' disease and primary hyperparathyroidism.SAGE open medical case reports · 2021Article
- Correlation of perioperative biochemical variables with single adenoma weight in patients with primary hyperparathyroidism.BMC surgery · 2020Article
- Intratumor heterogeneity in human parathyroid tumors.Histology and histopathology · 2020Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary hyperparathyroidism (pHPT) is a common endocrinopathy resulting from inappropriately high PTH secretion. It usually results from the presence of a single gland adenoma, multiple gland hyperplasia or rarely parathyroid carcinoma. All these conditions require different management, and it is important to be able to differentiate the underlined pathology, in order for the clinicians to provide the best therapeutic approach. Elucidation of the genetic background of each of these clinical entities would be of great interest. However, the molecular factors that control parathyroid tumorigenesis are poorly understood. There are data implicating the existence of specific genetic pathways involved in the emergence of parathyroid tumorigenesis. The main focus of the present study is to present the current optimal diagnostic and management protocols for pHPT as well as to review the literature regarding all molecular and genetic pathways that are to be involved in the pathophysiology of sporadic pHPT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.