Evidence map›Paper›PMID 29330301›Full record

ArticleThe Journal of biological chemistry2018

Genetic control of predominantly error-free replication through an acrolein-derived minor-groove DNA adduct.

Jung-Hoon Yoon, Richard P Hodge, Linda C Hackfeld, Jeseong Park, Jayati Roy Choudhury, Satya Prakash, Louise Prakash

Open access · hybridAbstract readComparative Study
In one paragraph

Article in The Journal of biological chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Mechanisms of DNA repair and mutagenesis induced by acetaldehyde, acrolein, aristolochic acids, and vinyl chloride.Journal of environmental science and health. Part C, Toxicology and carcinogenesis · 2025
    Review
  4. Article
  5. The Catalytic Activity of Human REV1 on Undamaged and Damaged DNA.International journal of molecular sciences · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jung-Hoon YoonDepartment of Biochemistry and Molecular Biology.
Richard P HodgeSealy Center for Environmental Health and Medicine, University of Texas Medical Branch at Galveston, Galveston, Texas 77555-1061.
Linda C HackfeldSealy Center for Environmental Health and Medicine, University of Texas Medical Branch at Galveston, Galveston, Texas 77555-1061.
Jeseong ParkDepartment of Biochemistry and Molecular Biology.
Jayati Roy ChoudhuryDepartment of Biochemistry and Molecular Biology.
Satya PrakashDepartment of Biochemistry and Molecular Biology.
Louise PrakashDepartment of Biochemistry and Molecular Biology. Electronic address: l.prakash@utmb.edu.
The University of Texas Medical Branch at Galveston · US

Funding

Synthetic Organic Chemistry CoreP30ES006676 · NIEHS · UNIVERSITY OF TEXAS MEDICAL BR GALVESTON · PI ELFERINK, CORNELIS JOHAN · 1995 to 2017
$21.7M
Role of cohesin in lesion bypass in DNA damaged human cellsR01ES022948 · NIEHS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI PRAKASH, LOUISE · 2014 to 2018
$1.7M
Genetic control of replication through DNA lesions in humans, and carcinogenesisR01ES020833 · NIEHS · UNIVERSITY OF TEXAS MED BR GALVESTON · PI PRAKASH, SATYA · 2012 to 2016
$1.7M
NIEHS NIH HHS P30 ES006676NIEHS NIH HHS R01 ES020833NIEHS NIH HHS R01 ES022948
6 · The paper itself

Abstract

Acrolein, an α,β-unsaturated aldehyde, is generated

Indexed as

DNA DamageDNA ReplicationAcroleinAmino Acid SubstitutionCell LineDeoxyguanosineDNA AdductsDNA-Directed DNA PolymeraseDNA Polymerase iotaEnvironmental PollutantsHumansMutagensMutationNuclear ProteinsNucleotidyltransferasesOrganophosphorus CompoundsAcroleinalpha-hydroxypropanodeoxyguanosineDeoxyguanosineDNA AdductsDNA-Directed DNA PolymeraseDNA Polymerase iotaEnvironmental PollutantsMutagensNuclear ProteinsNucleotidyltransferasesOrganophosphorus CompoundsphosphoramiditePOLI protein, humanPOLK protein, humanPOLN protein, humanRecombinant Fusion ProteinsRecombinant ProteinsREV1 protein, humanY-Family DNA PolymerasesDNA damageDNA damage responseDNA polymeraseDNA repairDNA replicationgamma-HOPdG(r) gamma-HOPdG phosphoramidite synthesistranslesion synthesis in human cells

Identifiers

PMID29330301
PMCPMC5827445
OpenAlexW2783901739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.