Evidence map›Paper›PMID 29330255›Full record

ArticleJournal of the American Heart Association2018

High-Intensity Cigarette Smoking Is Associated With Incident Diabetes Mellitus In Black Adults: The Jackson Heart Study.

Wendy B White, Loretta R Cain, Emelia J Benjamin, Andrew P DeFilippis, Michael J Blaha, Wei Wang, Victoria Okhomina, Rachel J Keith, Mahmoud Al Rifai, Sina Kianoush and 5 more

Open access · goldAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.

  1. Pooled it
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  8. Illicit Tobacco in Lithuania: A Cross-Sectional Survey.International journal of environmental research and public health · 2020
    Article
  9. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 8 institutions in 1 country.

Wendy B WhiteTougaloo College, Tougaloo, MS.
Loretta R CainDepartment of Data Sciences, University of Mississippi Medical Center, Jackson, MS.
Emelia J BenjaminDepartment of Medicine, Boston University School of Medicine, Boston, MA.
Andrew P DeFilippisDepartment of Medicine, University of Louisville, Louisville, KY.
Michael J BlahaCiccarone Center for the Prevention of Heart Disease, Johns Hopkins School of Medicine, Baltimore, MD.
Wei WangDepartment of Data Sciences, University of Mississippi Medical Center, Jackson, MS.
Victoria OkhominaDepartment of Data Sciences, University of Mississippi Medical Center, Jackson, MS.
Rachel J KeithDiabetes and Obesity Center, University of Louisville, Louisville, KY.
Mahmoud Al RifaiDepartment of Medicine, University of Kansas School of Medicine, Wichita, KS.
Sina KianoushCiccarone Center for the Prevention of Heart Disease, Johns Hopkins School of Medicine, Baltimore, MD.
Michael D WinnifordDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS.
Rose M RobertsonDepartment of Medicine, Vanderbilt University Medical Center, Nashville, TN.
Aruni BhatnagarDiabetes and Obesity Center, University of Louisville, Louisville, KY.
Adolfo CorreaDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS.
Michael E HallDepartment of Medicine, University of Mississippi Medical Center, Jackson, MS mehall@umc.edu.
University of Mississippi Medical Center · USUniversity of Louisville · USJohns Hopkins University · USJackson Memorial Hospital · USTougaloo College · USUniversity of Kansas · USUniversity School · USVanderbilt University Medical Center · US

Funding

The role of leptin in autoimmune-associated hypertensionP20GM104357 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI ALEXANDER, BARBARA T · 2013 to 2022
$23.4M
Research Training and Education Core (Core D) P50HL120163 · NHLBI · AMERICAN HEART ASSOCIATION · PI BHATNAGAR, ARUNI, ROBERTSON, ROSE MARIE · 2013 to 2017
$20.1M
Renal Sinus Fat, Hypertension, and Altered Kidney FunctionK08DK099415 · NIDDK · UNIVERSITY OF MISSISSIPPI MED CTR · PI HALL, MICHAEL EDWARD · 2015 to 2019
$791k
NHLBI NIH HHS HHSN268201300046CNHLBI NIH HHS HHSN268201300047CNHLBI NIH HHS HHSN268201300048CNHLBI NIH HHS HHSN268201300049CNHLBI NIH HHS HHSN268201300050CNHLBI NIH HHS P50 HL120163NIDDK NIH HHS K08 DK099415NIDDK NIH HHS L30 DK099913NIGMS NIH HHS P20 GM104357
6 · The paper itself

Abstract

backgroundPrevious reports on whether smoking is associated with insulin resistance and diabetes mellitus have yielded inconsistent findings. We aimed to evaluate the relationship between cigarette smoking and incident diabetes mellitus in the Jackson Heart Study. METHODS AND

resultsJackson Heart Study participants enrolled at baseline without prevalent diabetes mellitus (n=2991) were classified by self-report as current smokers, past smokers (smoked ≥400 cigarettes/life and no longer smoking), or never smokers. We quantified smoking intensity by number of cigarettes smoked daily; we considered ≥20 cigarettes per day (1 pack) "high-intensity." We defined diabetes mellitus as fasting glucose ≥126 mg/dL, hemoglobin A1c ≥6.5% or International Federation of Clinical Chemistry units HbA1c 48 mmol/mol, or use of diabetes mellitus medication. We estimated the adjusted associations of smoking status, intensity, and dose (pack-years) with incident diabetes mellitus using Poisson regression models. At baseline there were 361 baseline current (1-10 cigarettes per day [n=242]; ≥20 [n=119]), 502 past, and 2128 never smokers. From Visit 1 to Visit 3 (mean 8.0±0.9 years), 479 participants developed incident diabetes mellitus. After adjustment for covariates, baseline current smokers who smoked less than a pack/d and past smokers had similar rates of incident diabetes mellitus compared with never smokers (incidence rate ratios 1.04, 95% confidence interval, 0.69-1.58 and 1.08, 95% confidence interval, 0.82-1.42, respectively). Baseline current high-intensity smokers had a 79% (95% confidence interval, 1.14-2.81) higher incidence of diabetes mellitus compared with never smokers. Smoking dose (per 10 pack-years) was also associated with a higher incidence of diabetes mellitus (incidence rate ratios 1.10, 95% confidence interval, 1.03-1.19) in adjusted models.

conclusionsHigh-intensity cigarette smoking and smoking pack-years are associated with an increased risk of developing diabetes mellitus in blacks.

Indexed as

Black or African AmericanNon-SmokersSmokersAdiposityAdultAgedAged, 80 and overBiomarkersBlood GlucoseCigarette SmokingC-Reactive ProteinDiabetes MellitusFemaleGlycated HemoglobinHumansIncidenceBiomarkersBlood GlucoseC-Reactive ProteinGlycated Hemoglobinhemoglobin A1c protein, humandiabetes mellitusrace and ethnicitysmoking

Identifiers

PMID29330255
PMCPMC5850161
OpenAlexW2783619169

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.