Evidence map›Paper›PMID 29330178›Full record

ArticleApplied and environmental microbiology2018

Development of an Efficient Genome Editing Tool in Bacillus licheniformis Using CRISPR-Cas9 Nickase.

Kaifeng Li, Dongbo Cai, Zhangqian Wang, Zhili He, Shouwen Chen

Open access · bronzeAbstract read
In one paragraph

Article in Applied and environmental microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
5.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 98 citations in OpenAlex.

  1. Article
  2. Article
  3. Effects ofMicroorganisms · 2026
    Article
  4. Review
  5. Review
  6. Article
  7. Optimizing genome editing efficiency inApplied and environmental microbiology · 2025
    Article
  8. Current Approaches for Genetic Manipulation ofBiotech (Basel (Switzerland)) · 2025
    Review
  9. CRISPR-Cas9-driven genome editing inFrontiers in microbiology · 2025
    Article
  10. Establishment of the CRISPR-Cpf1 gene editing system inSynthetic and systems biotechnology · 2025
    Article
  11. AdvancingMicroorganisms · 2024
    Review
  12. Review
  13. Article
  14. CRISPR-Based Gene Editing inPharmaceuticals (Basel, Switzerland) · 2023
    Review
  15. Review
  16. Review
  17. Recent Advances in CRISPR-Cas Technologies for Synthetic Biology.Journal of microbiology (Seoul, Korea) · 2023
    Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Kaifeng LiState Key Laboratory of Agricultural Microbiology, College Life Science and Technology, Huazhong Agricultural University, Wuhan, China.
Dongbo CaiEnvironmental Microbial Technology Center of Hubei Province, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, College of Life Science, Hubei University, Wuhan, China.
Zhangqian WangEnvironmental Microbial Technology Center of Hubei Province, Hubei Collaborative Innovation Center for Green Transformation of Bio-Resources, College of Life Science, Hubei University, Wuhan, China.
Zhili HeState Key Laboratory of Agricultural Microbiology, College Life Science and Technology, Huazhong Agricultural University, Wuhan, China.
Shouwen ChenState Key Laboratory of Agricultural Microbiology, College Life Science and Technology, Huazhong Agricultural University, Wuhan, China mel212@126.com.
Hubei University · CNHuazhong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Bacillus licheniformisBacterial ProteinsCRISPR-Cas SystemsDeoxyribonuclease IGene EditingSubtilisinsBacterial ProteinsDeoxyribonuclease InattokinaseSubtilisinsBacillus licheniformisCRISPR-Cas9ndeletiongenome editingintegrationnattokinase production

Identifiers

PMID29330178
PMCPMC5835740
OpenAlexW2783755818

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.