ArticleBMC complementary and alternative medicine2018
Phytochemical analysis, antioxidant and anti-inflammatory potential of FERETIA APODANTHERA root bark extracts.
Article in BMC complementary and alternative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 56 citations in OpenAlex.
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- Ethnomedicinal Information on Plants Used for the Treatment of Bone Fractures, Wounds, and Sprains in the Northern Region of the Republic of Benin.Evidence-based complementary and alternative medicine : eCAM · 2022Article
- Antitumor Potential ofAntioxidants (Basel, Switzerland) · 2021Article
- Asphodelus tenuifolius extracts arrested inflammation and arthritis through modulation of TNF-α, NF-κB, ILs, and COX-2 activities in in vivo models.Inflammopharmacology · 2021Article
- Anti-inflammatory potential of dichloromethane leaf extracts ofAfrican health sciences · 2021Article
- Antimalarial, Antioxidant Activities and Chemoprofile ofAdvances in pharmacological and pharmaceutical sciences · 2021Article
- Bioassay-guided fractionation, phospholipase APharmaceutical biology · 2020Article
- Antilipoxygenase and Anti-Inflammatory Activities ofAdvances in pharmacological and pharmaceutical sciences · 2020Article
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- Antidengue potential of leaf extracts ofHeliyon · 2019Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInflammation has been implicated in many disorders, including cancer and available therapies elicit adverse effects. Plants of the family Rubiaceae have shown potency against inflammation. The anti-inflammatory and anti-oxidant potential of Feretia apodanthera was investigated in this study to evaluate its effectiveness.
methodsThe phytochemical, antioxidant and anti-inflammatory potential of root bark (n-Hexane, diethyl ether, ethanol and aqueous) extracts of Feretia apodanthera was investigated in this study. The extracts were subjected to various chemical tests for phytochemical constituents; their antioxidant activity was determined using in-vitro DPPH radical scavenging activity assay and their anti-inflammatory activity was determined using carrageenan induced paw oedema model. FTIR and GCMS analysis was done to determine the compounds present.
resultsPhytochemical screening of extracts revealed the presence of unsaturated steroids, triterpenes, cardiac glycosides, tannins, saponin and alkaloids. Vitamin C had a median inhibitory concentration (IC
conclusionThis study revealed that extracts of Feretia apodanthera possess anti-inflammatory effects against right hind paw oedema of albino rats and can act as an effective antioxidant.
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