Evidence map›Paper›PMID 29329208›Full record

ReviewCancers2018

Advances in Molecular Profiling and Categorisation of Pancreatic Adenocarcinoma and the Implications for Therapy.

Rille Pihlak, Jamie M J Weaver, Juan W Valle, Mairéad G McNamara

Registry-linked trialOpen access · goldAbstract readReview
In one paragraph

Review in Cancers, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05754788 (Identification of Gene Expression Profile Associated With Favorable Prognosis in Patients Undergoing Radical Surgery for Pancreatic and Ampullary Adenocarcinoma), which is not on this map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05754788 unknown statusnot on this mapstarted 2022, after this paper: background citation

Identification of Gene Expression Profile Associated With Favorable Prognosis in Patients Undergoing Radical Surgery for Pancreatic and Ampullary Adenocarcinoma

TypeobservationalSponsorFondazione IRCCS Istituto Nazionale dei Tumori, MilanoRan2022 to 2023Enrolled40ConditionsResectable Pancreatic Adenocarcinoma
3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Rille PihlakDivision of Cancer Sciences, University of Manchester, Manchester M13 9NT, UK. rille.pihlak@christie.nhs.uk.
Jamie M J WeaverDepartment of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester M20 4BX, UK. Jamie.Weaver@christie.nhs.uk.
Juan W ValleDivision of Cancer Sciences, University of Manchester, Manchester M13 9NT, UK. juan.valle@christie.nhs.uk.
Mairéad G McNamaraDivision of Cancer Sciences, University of Manchester, Manchester M13 9NT, UK. Mairead.McNamara@christie.nhs.uk.
The Christie NHS Foundation Trust · GBUniversity of Manchester · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic ductal adenocarcinoma (PDAC) continues to be a disease with poor outcomes and short-lived treatment responses. New information is emerging from genome sequencing identifying potential subgroups based on somatic and germline mutations. A variety of different mutations and mutational signatures have been identified; the driver mutation in around 93% of PDAC is

Indexed as

clinical implicationsmolecular profilingmutationspancreatic adenocarcinoma

Identifiers

PMID29329208
PMCPMC5789367
OpenAlexW2783872613

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.