Evidence map›Paper›PMID 29329048›Full record

ArticlePsychiatry research2018

Characterizing anger-related affect in individuals with posttraumatic stress disorder using ecological momentary assessment.

Elizabeth E Van Voorhees, Paul A Dennis, Eric B Elbogen, Bernard Fuemmeler, Lydia C Neal, Patrick S Calhoun, Jean C Beckham

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Psychiatry research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04051320 (Characterizing the Neural Substrates of Irritability in Women), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.0field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04051320 phase2completednot on this mapstarted 2020, after this paper: background citation

Characterizing the Neural Substrates of Irritability in Women: an Experimental Neuroendocrine Model

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2020 to 2022Enrolled23ConditionsPerinatal Depression, Post Partum Depression, Depression, Postpartum, DepressionArmsLeuprolide Acetate 3.75 MG/ML, Estradiol 2 Mg tablet, Micronized progesterone
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
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  6. Scoping Review of Experience Sampling Methodology Investigations of Posttraumatic Stress Disorder Symptoms.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Elizabeth E Van VoorheesDurham Veterans Affairs Medical Center, United States; VISN 6, Mental Illness Research, Education and Clinical Center (MIRECC), Durham, NC, United States; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States. Electronic address: e.vanv@duke.edu.
Paul A DennisDurham Veterans Affairs Medical Center, United States; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Eric B ElbogenDurham Veterans Affairs Medical Center, United States; VISN 6, Mental Illness Research, Education and Clinical Center (MIRECC), Durham, NC, United States; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Bernard FuemmelerDepartment of Health Behavior and Policy School of Medicine, Virginia Commonwealth University, Richmond, VA, United States.
Lydia C NealDurham Veterans Affairs Medical Center, United States; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Patrick S CalhounDurham Veterans Affairs Medical Center, United States; VISN 6, Mental Illness Research, Education and Clinical Center (MIRECC), Durham, NC, United States; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Jean C BeckhamDurham Veterans Affairs Medical Center, United States; VISN 6, Mental Illness Research, Education and Clinical Center (MIRECC), Durham, NC, United States; Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Duke University Hospital · USDurham VA Medical Center · USDuke Medical Center · USMental Illness Research, Education and Clinical Centers · USVirginia Commonwealth University · US

Funding

Smoking & Anxiety In Posttraumatic Stress DisorderR01CA081595 · NCI · DUKE UNIVERSITY · PI BECKHAM, JEAN C. · 1998 to 2010
$1.4M
Group Cognitive Behavioral Therapy for Anger and Aggression in Veterans with PTSDIK2RX001298 · VA · DURHAM VA MEDICAL CENTER · PI VAN VOORHEES, ELIZABETH · 2015 to 2018
–
NCI NIH HHS R01 CA081595RRD VA IK2 RX001298
6 · The paper itself

Abstract

This study employed secondary analyses of existing ecological momentary assessment (EMA) data to characterize hostile and irritable affect in the day-to-day experience of 52 smokers with, and 65 smokers without, posttraumatic stress disorder (PTSD). EMA monitoring occurred over a mean of 8.2 days, and participants responded to an average of 2.8 random prompts/day. Analyses included Wilcoxon rank sum tests of group differences, and path analyses of cross-lagged multilevel models. Participants with PTSD endorsed a significantly higher proportion of total EMA entries indicating hostile affect and irritable affect than did individuals without PTSD. Cross-lagged analyses indicated that over a period of hours, PTSD symptoms significantly predicted subsequent hostile and irritable affect, but hostile and irritable affect did not predict subsequent PTSD symptoms. Findings suggest that day-to-day exposure to PTSD-related trauma cues may contribute to chronically elevated levels of anger-related affect. Such heightened affective arousal may, in turn, underlie an increased risk for verbal or physical aggression, as well as other health and quality-of-life related impairments associated with PTSD. Clinical implications include conceptualizing anger treatment in the broader context of trauma history and symptoms, and specifically targeting physiological arousal and maladaptive hostile cognitions triggered by trauma reminders in patients with PTSD.

Indexed as

AngerHostilityIrritable MoodAdultAggressionArousalEcological Momentary AssessmentFemaleHumansMaleMiddle AgedStress Disorders, Post-TraumaticVeteransArousal dysregulationHostilityIrritabilityVeterans

Identifiers

PMID29329048
PMCPMC6341481
OpenAlexW2781934722

What OpenQuestion holds

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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.