Evidence map›Paper›PMID 29328690›Full record

ArticlePhysical review letters2017

One-Parameter Scaling Theory for DNA Extension in a Nanochannel.

E Werner, G K Cheong, D Gupta, K D Dorfman, B Mehlig

Open access · hybridAbstract read
In one paragraph

Article in Physical review letters, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Nanoplumbing with 2D Metamaterials.Small (Weinheim an der Bergstrasse, Germany) · 2019
    Article
  6. Article
  7. Alpha-Synuclein Modulates the Physical Properties of DNA.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018
    Article
  8. Measuring the wall depletion length of nanoconfined DNA.The Journal of chemical physics · 2018
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

E WernerDepartment of Physics, University of Gothenburg, SE-41296 Gothenburg, Sweden.
G K CheongDepartment of Chemical Engineering and Materials Science, University of Minnesota-Twin Cities, 421 Washington Avenue SE, Minneapolis, Minnesota 55455, USA.
D GuptaDepartment of Chemical Engineering and Materials Science, University of Minnesota-Twin Cities, 421 Washington Avenue SE, Minneapolis, Minnesota 55455, USA.
K D DorfmanDepartment of Chemical Engineering and Materials Science, University of Minnesota-Twin Cities, 421 Washington Avenue SE, Minneapolis, Minnesota 55455, USA.
B MehligDepartment of Physics, University of Gothenburg, SE-41296 Gothenburg, Sweden.
University of Minnesota · USUniversity of Gothenburg · SE

Funding

Dynamics of DNA Barcoding in NanochannelsR01HG006851 · NHGRI · UNIVERSITY OF MINNESOTA · PI DORFMAN, KEVIN D · 2013 to 2018
$2.1M
NHGRI NIH HHS R01 HG006851
6 · The paper itself

Abstract

Experiments measuring DNA extension in nanochannels are at odds with even the most basic predictions of current scaling arguments for the conformations of confined semiflexible polymers such as DNA. We show that a theory based on a weakly self-avoiding, one-dimensional "telegraph" process collapses experimental data and simulation results onto a single master curve throughout the experimentally relevant region of parameter space and explains the mechanisms at play.

Indexed as

Models, TheoreticalNanostructuresDNAModels, MolecularNanotechnologyPolymersDNAPolymers

Identifiers

PMID29328690
PMCPMC5769985
OpenAlexW2781061230

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.