Evidence map›Paper›PMID 29327945›Full record

ArticleThe British journal of radiology2018

The gas bubble sign-a reliable indicator of laryngeal fractures in hanging on post-mortem CT.

Katja Schulze, Lars Christian Ebert, Thomas Daniel Ruder, Barbara Fliss, Sebastian Alexander Poschmann, Dominic Gascho, Michael Josef Thali, Patricia Mildred Flach

Open access · greenAbstract read
In one paragraph

Article in The British journal of radiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Death by hanging: possibilities and limits of medico-legal evidence.International journal of legal medicine · 2026
    Review
  5. A scoping review of strangulation and hanging: determining suicide from concealed homicide in equivocal death cases.Psychiatry, psychology, and law : an interdisciplinary journal of the Australian and New Zealand Association of Psychiatry, Psychology and Law · 2026
    Article
  6. Article
  7. Article
  8. Postmortem CT: Applications in Clinical and Forensic Medicine.Radiographics : a review publication of the Radiological Society of North America, Inc · 2025
    Review
  9. The current state of forensic imaging - post mortem imaging.International journal of legal medicine · 2025
    Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Katja Schulze1 Institute of Forensic Medicine and Imaging, University of Zurich , Zurich , Switzerland.
Lars Christian Ebert1 Institute of Forensic Medicine and Imaging, University of Zurich , Zurich , Switzerland.
Thomas Daniel Ruder1 Institute of Forensic Medicine and Imaging, University of Zurich , Zurich , Switzerland.
Barbara Fliss1 Institute of Forensic Medicine and Imaging, University of Zurich , Zurich , Switzerland.
Sebastian Alexander Poschmann1 Institute of Forensic Medicine and Imaging, University of Zurich , Zurich , Switzerland.
Dominic Gascho1 Institute of Forensic Medicine and Imaging, University of Zurich , Zurich , Switzerland.
Michael Josef Thali1 Institute of Forensic Medicine and Imaging, University of Zurich , Zurich , Switzerland.
Patricia Mildred Flach1 Institute of Forensic Medicine and Imaging, University of Zurich , Zurich , Switzerland.
University of Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose was to evaluate the presence of gas in the tissue adjacent to the laryngeal structures, "the gas bubble sign", in cases of hanging as a diagnostic indicator of neck trauma.

methodsIn this study, post-mortem CT (PMCT) scans and autopsies of 35 victims of hanging were examined to reveal age-dependent changes, laryngeal fracture, fracture location and the presence of gas. A matched group with cardiac arrest or intoxication was used as controls (n = 35). An autopsy was performed in each case.

resultsIncomplete suspension was the most common method in hanging. The thyroid horns (90.5%) were identified as the most vulnerable location for fractures. Laryngeal deformity and dislocation, which was only detected on PMCT, was observed in 57.1% and was concomitant with fractures in 83.3%. Laryngeal fractures are more common with advanced age (>40 years, 88.9%) and less common in younger subjects (<40 years, 29.4%). The gas bubble sign with regard to laryngeal fractures yielded a sensitivity of 79.2%, a positive predictive value of 95%, a specificity of 90.9%, a negative predictive value of 34.5% and an accuracy of 83%.

conclusionThe complex evaluation of the larynx is profoundly supported by PMCT and the detection of the gas bubble sign as a diagnostic indicator of neck trauma. This relevant diagnostic finding might aid in not only post-mortem cases but also clinical cases, for patients who survive an assault to the neck. Advances in knowledge: (1) The gas bubble sign is a diagnostic indicator of neck trauma in not putrefied bodies. (2) PMCT supports evaluation of trauma to the neck in hanging tremendously. (3) The diagnostic finding of gas located at the laryngeal structures may not only aid in post-mortem cases but also clinical cases of people who survive an assault to the neck.

Indexed as

AsphyxiaAutopsyGasesTomography, X-Ray ComputedAdultAgedCause of DeathFemaleFractures, BoneHumansHyoid BoneImaging, Three-DimensionalLarynxMaleMiddle AgedSensitivity and SpecificityGases

Identifiers

PMID29327945
PMCPMC5966003
OpenAlexW2783142570

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.