Evidence map›Paper›PMID 29327429›Full record

ArticleJournal of tissue engineering and regenerative medicine2018

In vivo migration of endogenous brain progenitor cells guided by an injectable peptide amphiphile biomaterial.

Reza Motalleb, Eric J Berns, Piyush Patel, Julie Gold, Samuel I Stupp, H Georg Kuhn

Abstract read
In one paragraph

Article in Journal of tissue engineering and regenerative medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.4field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 38 citations in OpenAlex.

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  13. Bioinspired neuron-like electronics.Nature materials · 2019
    Article
  14. Article
  15. Role of Extracellular Matrix in Development and Cancer Progression.International journal of molecular sciences · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Reza MotallebCenter for Brain Repair and Rehabilitation, Institute for Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-8330-8697
Eric J BernsDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
Piyush PatelCenter for Brain Repair and Rehabilitation, Institute for Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.
Julie GoldDepartment of Applied Physics, Biological Physics, Chalmers University of Technology, Gothenburg, Sweden.
Samuel I StuppDepartment of Biomedical Engineering, Northwestern University, Evanston, IL, USA.
H Georg KuhnCenter for Brain Repair and Rehabilitation, Institute for Neuroscience and Physiology, University of Gothenburg, Gothenburg, Sweden.
Northwestern University · USUniversity of Gothenburg · SEChalmers University of Technology · SECharité - Universitätsmedizin Berlin · DE

Funding

Regenerative Scaffold Technologies for CNS and DiabetesR01EB003806 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI STUPP, SAMUEL I · 2004 to 2015
$10.7M
NIBIB NIH HHS R01 EB003806
6 · The paper itself

Abstract

Biomaterials hold great promise in helping the adult brain regenerate and rebuild after trauma. Peptide amphiphiles (PAs) are highly versatile biomaterials, gelling and forming macromolecular structures when exposed to physiological levels of electrolytes. We are here reporting on the first ever in vivo use of self-assembling PA carrying a Tenascin-C signal (E

Indexed as

AnimalsBiocompatible MaterialsBrain InjuriesCell MovementDoublecortin ProteinMaleMicrogliaNanofibersNeocortexNeural Stem CellsPeptidesRatsRats, Sprague-DawleyTenascinBiocompatible MaterialsDcx protein, ratDoublecortin ProteinPeptidesTenascincell migrationdoublecortinnanofiber hydrogelpeptide amphiphilerostral migratory streamTenascin-C

Identifiers

PMID29327429
PMCPMC6028017
OpenAlexW2783055192

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.