Evidence map›Paper›PMID 29327212›Full record

Observational studyJournal of general internal medicine2018

A Composite of Functional Status and Pneumonia Severity Index Improves the Prediction of Pneumonia Mortality in Older Patients.

Francisco Sanz, María Morales-Suárez-Varela, Estrella Fernández, Luis Force, María José Pérez-Lozano, Vicente Martín, Mikel Egurrola, Jesús Castilla, Jenaro Astray, Diana Toledo and 2 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in Journal of general internal medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Review
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. The situation of infection in the elderly in Spain: a multidisciplinary opinion document.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2020
    Article
  14. Community-acquired pneumonia in critically ill very old patients: a growing problem.European respiratory review : an official journal of the European Respiratory Society · 2020
    Review
  15. Observational
  16. Observational
  17. Review
  18. Article
  19. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Francisco SanzConsorci Hospital General Universitari de València, València, Spain. sanz_fraher@gva.es.
María Morales-Suárez-VarelaUniversitat de València, València, Spain.
Estrella FernándezConsorci Hospital General Universitari de València, València, Spain.
Luis ForceHospital de Mataró, Mataró, Spain.
María José Pérez-LozanoHospital Universitario Virgen de Valme, Sevilla, Spain.
Vicente MartínUniversidad de León, León, Spain.
Mikel EgurrolaHospital de Galdakao, Usansolo, Spain.
Jesús CastillaCIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Jenaro AstrayConsejería de Sanidad, Madrid, Spain.
Diana ToledoCIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Ángela DomínguezCIBER Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.
Project PI12/02079 Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe baseline health status may be a determinant of interest in the evolution of pneumonia.

objectiveOur objective was to assess the predictive ability of community-acquired pneumonia (CAP) mortality by combining the Barthel Index (BI) and Pneumonia Severity Index (PSI) in patients aged ≥ 65 years. DESIGN, PATIENTS AND MAIN MEASURES: In this prospective, observational, multicenter analysis of comorbidities, the clinical data, additional examinations and severity of CAP were measured by the PSI and functional status by the BI. Two multivariable models were generated: Model 1 including the PSI and BI and model 2 with PSI plus BI stratified categorically. KEY

resultsThe total population was 1919 patients, of whom 61% had severe pneumonia (PSI IV-V) and 40.4% had some degree of dependence (BI ≤ 90 points). Mortality in the PSI V-IV group was 12.5%. Some degree of dependence was associated with increased mortality in both the mild (7.2% vs. 3.2%; p = 0.016) and severe (14% vs. 3.3%; p < 0.001) pneumonia groups. The combination of PSI IV-V and BI ≤ 90 was the greatest risk factor for mortality (aOR 4.17; 95% CI 2.48 to 7.02) in our series.

conclusionsThe use of a bimodal model to assess CAP mortality (PSI + BI) provides more accurate prognostic information than the use of each index separately.

Indexed as

Severity of Illness IndexAgedAged, 80 and overCommunity-Acquired InfectionsFemaleHospitalizationHumansMaleMortalityPneumoniaPredictive Value of TestsProspective Studiescommunity-acquired pneumoniafunctional statusseverity assessment

Identifiers

PMID29327212
PMCPMC5880765

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.