Evidence map›Paper›PMID 29327182›Full record

ArticleObesity surgery2018

Changes in Iron Absorption After Roux-en-Y Gastric Bypass.

Wendy Schijns, Marjolein A P Ligthart, Frits J Berends, Ignace M C Janssen, Cees J H M van Laarhoven, Edo O Aarts, Hans de Boer

Abstract read
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Article in Obesity surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Acquired Refractory Iron Deficiency Anemia.Mediterranean journal of hematology and infectious diseases · 2021
    Review
  3. The role of alimentary and biliopancreatic limb length in outcomes of Roux-en-Y gastric bypass.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wendy SchijnsDepartment of Surgery, Rijnstate Hospital, Postal number 1190, 6800, TA, Arnhem, The Netherlands. wschijns@rijnstate.nl.ORCID 0000-0002-2752-7246
Marjolein A P LigthartDepartment of Surgery, Rijnstate Hospital, Postal number 1190, 6800, TA, Arnhem, The Netherlands.
Frits J BerendsDepartment of Surgery, Rijnstate Hospital, Postal number 1190, 6800, TA, Arnhem, The Netherlands.
Ignace M C JanssenDepartment of Surgery, Rijnstate Hospital, Postal number 1190, 6800, TA, Arnhem, The Netherlands.
Cees J H M van LaarhovenDepartment of Surgery, Radboud UMC, Nijmegen, The Netherlands.
Edo O AartsDepartment of Surgery, Rijnstate Hospital, Postal number 1190, 6800, TA, Arnhem, The Netherlands.
Hans de BoerDepartment of Internal Medicine, Rijnstate Hospital, Arnhem, The Netherlands.
Rijnstate Hospital · NLRadboud University Nijmegen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIron deficiency is one of the most common deficiencies that may occur after Roux-en-Y gastric bypass (RYGB). Little is known about the optimal treatment of post-RYGB iron deficiency.

aimThe aim of this study is to evaluate the changes in iron absorption characteristics after RYGB for two oral iron formulations, one presented in tablet form and one as in the form of a solution.

methodIron absorption in 24 obese women was studied before and 1 month after RYGB. Twelve patients were tested with a single dose of 600 mg ferrous fumarate in tablet form (195 mg of elementary iron, group 1), and 12 patients received a single dose of 1390 mg ferrous gluconate as a solution (160 mg of elementary iron, group 2). Serum iron levels were measured before (T

resultsBefore surgery, iron absorption was similar for the two supplements (P = 0.71). However, RYGB was associated with a decrease in fumarate iron absorption (P < 0.001) but did not affect gluconate iron absorption (P = 0.13). Postoperative absorption of fumarate iron was significantly lower than gluconate iron at T1 (P < 0.05), but the overall difference over 9 h did not reach statistical significance (P = 0.53).

conclusionRYGB adversely affects the absorption of ferrous fumarate tablets but not that of solubilized ferrous gluconate. A solubilized supplement is therefore preferred as the supplement of first choice after RYGB.

Indexed as

Gastric BypassIronDietary SupplementsFemaleFerrous CompoundsHumansIron DeficienciesObesity, MorbidFerrous Compoundsferrous gluconateIronAbsorptionDeficiencyFerritinIronMorbid obesityRoux-en-Y gastric bypass

Identifiers

PMID29327182
OpenAlexW2783512526

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.