Evidence map›Paper›PMID 29326962›Full record

ReviewMolecular therapy. Methods & clinical development2018

Emerging Issues in AAV-Mediated

Pasqualina Colella, Giuseppe Ronzitti, Federico Mingozzi

Abstract readReview
In one paragraph

Review in Molecular therapy. Methods & clinical development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 535 papers.

0numbers the graph read from it
0cells of the map it votes in
535citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

535 citing papers in PubMed.

  1. Adeno-Associated Viral Vector (AAV)-Mediated In Vivo CRISPR-Cas9 Delivery.Methods in molecular biology (Clifton, N.J.) · 2027
    Article
  2. Towards mRNA therapeutics 2.0.Nature reviews. Drug discovery · 2026
    Review
  3. Article
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  5. Review
  6. Article
  7. Epigenetic regulation of transgenes.Journal of biotechnology · 2026
    Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Monoclonal Antibodies Targeting Bacterial Infections: A Broad Review of the Field.BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy · 2026
    Review
  18. Article
  19. Article
  20. Review

475 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pasqualina ColellaGenethon, INSERM U951 INTEGRARE, University of Evry, University Paris-Saclay, 91001 Evry, France.
Giuseppe RonzittiGenethon, INSERM U951 INTEGRARE, University of Evry, University Paris-Saclay, 91001 Evry, France.
Federico MingozziGenethon, INSERM U951 INTEGRARE, University of Evry, University Paris-Saclay, 91001 Evry, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, the number of clinical trials in which adeno-associated virus (AAV) vectors have been used for

Indexed as

AAVAAV capsidAAV genomegene therapygenotoxicityinherited diseasesliver immunogenicitypersistence

Identifiers

PMID29326962
PMCPMC5758940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.