ArticleOpen forum infectious diseases2018
Use of Antibiotic Prophylaxis for Tooth Extractions, Dental Implants, and Periodontal Surgical Procedures.
Article in Open forum infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 55 citations in OpenAlex.
- Infectious complications of dental procedures in dogs and cats, and the impact of antimicrobial prophylaxis: a systematic review.The Journal of small animal practice · 2026Pooled it
- Bioregulatory periodontal medicine: could the molecular networks, inflammation and system biology modify the auto-regulatory capacity of the patients?Frontiers in physiology · 2026Pooled it
- Evidence-based clinical practice guideline on antibiotic use for the urgent management of pulpal- and periapical-related dental pain and intraoral swelling: A report from the American Dental Association.Journal of the American Dental Association (1939) · 2019Guideline
- Randomized controlled trial comparing antibiotics to placebo for single simple dental extractions in diabetic patients.Acta odontologica latinoamericana : AOL · 2025Trial
- A Systematic Review on Prior/Postoperative Antibiotics Therapy Efficiency in Reducing Surgical Complications After Third Molar Extraction Surgery.Journal of maxillofacial and oral surgery · 2025Review
- Optimal Duration of Antibiotic Therapy for Space Infections in the Maxillofacial Region: A Systematic Review.Craniomaxillofacial trauma & reconstruction · 2025Review
- Factors associated with antibiotic use patterns in Thailand after COVID-19.Scientific reports · 2025Article
- Prophylactic antibiotic use is common in dogs and cats presenting for procedures at veterinary referral dental practices.Journal of the American Veterinary Medical Association · 2025Article
- Systematic Review Protocol on Antibiotic Use for infection related Orofacial Pain: Policy and Practice Implications.F1000Research · 2025Article
- Article
- Antibiotic prophylaxis dysregulates dental implant placement surgery-induced osteoimmune wound healing and attenuates the alveolar bone-implant interface in mice.Journal of clinical periodontology · 2023Article
- Comparison of guideline concordant antibiotic prophylaxis in Veterans Affairs and non-Veterans Affairs dental settings among those with cardiac conditions or prosthetic joints.BMC infectious diseases · 2023Article
- Antimicrobial use practices in canine and feline dental procedures performed in primary care veterinary practices in the United States.PloS one · 2023Article
- Private Practice Dentists Improve Antibiotic Use After Dental Antibiotic Stewardship Education From Infectious Diseases Experts.Open forum infectious diseases · 2022Article
- Evaluation of antibiotic prescribing for ambulatory patients seeking primary dental care services in a public hospital in Ghana: a clinical audit study.JAC-antimicrobial resistance · 2022Article
- Severe infections after teeth removal - are we doing enough in preventing them?Journal of clinical and experimental dentistry · 2022Article
- Antibiotic Prescribing Knowledge, Awareness, and Attitude of Dental Surgeons Practicing in the Urban Indian Population.Journal of pharmacy & bioallied sciences · 2021Article
- Endodontic Infections and the Extent of Antibiotic Overprescription among Italian Dental Practitioners.Antimicrobial agents and chemotherapy · 2021Article
- Preventive Antibiotic Prescribing Habits among Professionals Dedicated to Oral Implantology: An Observational Study.Antibiotics (Basel, Switzerland) · 2021Article
- Current antimicrobial prescription at outpatient dentistry centers and clinics in tertiary-care hospitals in Tokyo, Japan: A multicenter cross-sectional study.Antimicrobial stewardship & healthcare epidemiology : ASHE · 2021Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundGuidelines for antibiotics prior to dental procedures for patients with specific cardiac conditions and prosthetic joints have changed, reducing indications for antibiotic prophylaxis. In addition to guidelines focused on patient comorbidities, systematic reviews specific to dental extractions and implants support preprocedure antibiotics for all patients. However, data on dentist adherence to these recommendations are scarce.
methodsThis was a cross-sectional study of veterans undergoing tooth extractions, dental implants, and periodontal procedures. Patients receiving antibiotics for oral or nonoral infections were excluded. Data were collected through manual review of the health record.
resultsOf 183 veterans (mean age, 62 years; 94.5% male) undergoing the included procedures, 82.5% received antibiotic prophylaxis (mean duration, 7.1 ± 1.6 days). Amoxicillin (71.3% of antibiotics) and clindamycin (23.8%) were prescribed most frequently; 44.7% of patients prescribed clindamycin were not labeled as penicillin allergic. Of those who received prophylaxis, 92.1% received postprocedure antibiotics only, 2.6% received preprocedural antibiotics only, and 5.3% received pre- and postprocedure antibiotics. When prophylaxis was indicated, 87.3% of patients received an antibiotic. However, 84.9% received postprocedure antibiotics when preprocedure administration was indicated. While the majority of antibiotics were indicated, only 8.2% of patients received antibiotics appropriately. The primary reason was secondary to prolonged duration. Three months postprocedure, there were no occurrences of
conclusionThe majority of patients undergoing a dental procedure received antibiotic prophylaxis as indicated. Although patients for whom antibiotic prophylaxis was indicated should have received a single preprocedure dose, most antibiotics were prescribed postprocedure. Dental stewardship efforts should ensure appropriate antibiotic timing, indication, and duration.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.