Evidence map›Paper›PMID 29326949›Full record

ArticleFrontiers in veterinary science2017

Molecular Characterization and Cluster Analysis of Field Isolates of Avian Infectious Laryngotracheitis Virus from Argentina.

María I Craig, Maria F Rojas, Claudia A van der Ploeg, Valeria Olivera, Ariel E Vagnozzi, Andrés M Perez, Guido A König

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 26 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 3 countries.

María I CraigInstituto de Virología, Centro de Investigación en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria (INTA)-Hurlingham, Buenos Aires, Argentina.
Maria F RojasLaboratorio de Sanidad Aviar, Estación Experimental Agropecuaria, Instituto Nacional de Tecnología Agropecuaria (INTA)-Concepción del Uruguay, Entre Rios, Argentina.
Claudia A van der PloegInstituto Nacional de Producción de Biológicos, ANLIS "Dr. Carlos G. Malbrán", Ciudad de Buenos Aires, Argentina.
Valeria OliveraInstituto de Virología, Centro de Investigación en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria (INTA)-Hurlingham, Buenos Aires, Argentina.
Ariel E VagnozziInstituto de Virología, Centro de Investigación en Ciencias Veterinarias y Agronómicas, Instituto Nacional de Tecnología Agropecuaria (INTA)-Hurlingham, Buenos Aires, Argentina.
Andrés M PerezDepartment of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN, United States.
Guido A KönigInstituto de Biotecnología, Centro de Investigación en Ciencias Veterinarias y Agronómicas INTA-Hurlingham, Buenos Aires, Argentina.
National Agricultural Technology Institute · ARNational Institute of Industrial Technology · ARAdministración Nacional de Laboratorios e Institutos de Salud · ARConsejo Nacional de Investigaciones Científicas y Técnicas · ARUniversity of Minnesota · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Avian infectious laryngotracheitis (ILT) is a worldwide infectious disease that causes important economic losses in the poultry industry. Although it is known that ILT virus (ILTV) is present in Argentina, there is no information about the circulating strains. With the aim to characterize them, seven different genomic regions (thymidine kinase, glycoproteins D, G, B, C, and J, and infected cell polypeptide 4) were partially sequenced and compared between field samples. The gJ sequence resulted to be the most informative segment, it allowed the differentiation among field sample strains, and also, between wild and vaccine viruses. Specific changes in selected nucleotidic positions led to the definition of five distinct haplotypes. Tests for detection of clustering were run to test the null hypothesis that ILTV haplotypes were randomly distributed in time in Argentina and in space in the most densely populated poultry region of this country, Entre Rios. From this study, it was possible to identify a 46 km radius cluster in which higher proportions of haplotypes 4 and 5 were observed, next to a provincial route in Entre Rios and a significant decline of haplotype 5 between 2009 and 2011. Results here provide an update on the molecular epidemiology of ILT in Argentina, including data on specific genome segments that may be used for rapid characterization of the virus in the field. Ultimately, results will contribute to the surveillance of ILT in the country.

Indexed as

Argentinaepidemiologyglycoprotein Jinfectious laryngotracheitis virusmolecular characterizationspatial cluster analysis

Identifiers

PMID29326949
PMCPMC5733342
OpenAlexW2773835457

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.