ArticleMediterranean journal of hematology and infectious diseases2018
Molecular Heterogeneity in Acute Promyelocytic Leukemia - a Single Center Experience from India.
Article in Mediterranean journal of hematology and infectious diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Identification of a novel PML exon 6 splice variant in atypical PML::RARα transcripts in acute promyelocytic leukemia.Annals of hematology · 2025Article
- The Frequency, Clinico-Hematological Features, and Outcome of Acute Promyelocytic Leukemia with VariantIndian journal of hematology & blood transfusion : an official journal of Indian Society of Hematology and Blood Transfusion · 2024Article
- Spinal myeloid sarcoma presenting as initial symptom in acute promyelocytic leukemia with a rare crypticFrontiers in oncology · 2024Article
- Immunophenotypic characterization of acute leukemias in Bahia, Brazil.Einstein (Sao Paulo, Brazil) · 2023Article
- [Analysis of fusion gene expression in acute myeloid leukemia].Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi · 2021Article
- PLZF-RARCancers · 2020Review
- Review
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16 authors.
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Abstract
Atypical breakpoints and variant APL cases involving alternative chromosomal aberrations are seen in a small subset of acute promyelocytic leukemia (APL) patients. Over seven different partner genes for RARA have been described. Although rare, these variants prove to be a diagnostic challenge and require a combination of advanced cytogenetic and molecular techniques for accurate characterization. Heterogeneity occurs not only at the molecular level but also at clinico-pathological level influencing treatment response and outcome. In this case series, we describe the molecular heterogeneity of APL with a focus on seven variant APL cases from a single tertiary cancer center in India over a period of two and a half years. We discuss five cases with
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