Evidence map›Paper›PMID 29326725›Full record

ArticleFrontiers in immunology2017

Anti-inflammatory Effects of Heme Oxygenase-1 Depend on Adenosine A

Franziska M Konrad, Constantin Zwergel, Kristian-Christos Ngamsri, Jörg Reutershan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 20 citations in OpenAlex.

  1. A clinician's musings on oxygen: Too little or too much with life in the balance.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Article
  2. Review
  3. Review
  4. Article
  5. Heme, Heme Oxygenase-1, Statins, and SARS-CoV-2.Antioxidants (Basel, Switzerland) · 2023
    Article
  6. Article
  7. The Impact of Hypoxia in Early Pregnancy on Placental Cells.International journal of molecular sciences · 2021
    Review
  8. Adenosine and Inflammation: Here, There and Everywhere.International journal of molecular sciences · 2021
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Franziska M KonradDepartment of Anesthesiology and Intensive Care Medicine, University Hospital of Tübingen, Tübingen, Germany.
Constantin ZwergelDepartment of Anesthesiology and Intensive Care Medicine, University Hospital of Tübingen, Tübingen, Germany.
Kristian-Christos NgamsriDepartment of Anesthesiology and Intensive Care Medicine, University Hospital of Tübingen, Tübingen, Germany.
Jörg ReutershanDepartment of Anesthesiology and Intensive Care Medicine, Hospital of Bayreuth, Bayreuth, Germany.
University Children's Hospital Tübingen · DEBayreuth Medical Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute pulmonary inflammation is still a frightening complication in intensive care units. In our previous study, we determined that heme oxygenase (HO)-1 had anti-inflammatory effects in pulmonary inflammation. Recent literature has emphasized a link between HO-1 and the nucleotide adenosine. Since adenosine A

Indexed as

heme oxygenase-1heminneutrophilPMNpulmonary inflammation

Identifiers

PMID29326725
PMCPMC5742329
OpenAlexW2781196765

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.