Evidence map›Paper›PMID 29326718›Full record

ArticleFrontiers in immunology2017

Deletion of TGF-β1 Increases Bacterial Clearance by Cytotoxic T Cells in a Tuberculosis Granuloma Model.

Hayley C Warsinske, Elsje Pienaar, Jennifer J Linderman, Joshua T Mattila, Denise E Kirschner

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 55 citations in OpenAlex.

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  10. Experimental dissection of tuberculosis protective immunity: a human perspective.Frontiers in cellular and infection microbiology · 2025
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  16. The impact ofFrontiers in immunology · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Hayley C WarsinskeDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, United States.
Elsje PienaarDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, United States.
Jennifer J LindermanDepartment of Chemical Engineering, University of Michigan, Ann Arbor, MI, United States.
Joshua T MattilaDepartment of Infectious Diseases and Microbiology, University of Pittsburgh Graduate School of Public Health, Pittsburgh, PA, United States.
Denise E KirschnerDepartment of Microbiology and Immunology, University of Michigan Medical School, Ann Arbor, MI, United States.
University of Michigan–Ann Arbor · USUniversity of Pittsburgh · US

Funding

Predicting immune responses that correlate with protection against tuberculosisR01HL110811 · NHLBI · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FLYNN, JOANNE L., KIRSCHNER, DENISE E · 2012 to 2016
$5.9M
Predicting protective T-cell responses in Tuberculosis using a systems biology approachR01AI123093 · NIAID · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FLYNN, JOANNE L., KIRSCHNER, DENISE E · 2016 to 2020
$3.6M
A Multi-scale systems pharmacology approach to TB therapyU01HL131072 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI DARTOIS, VERONIQUE, FLYNN, JOANNE L. · 2016 to 2019
$2.9M
NHLBI NIH HHS R01 HL110811NHLBI NIH HHS U01 HL131072NIAID NIH HHS R01 AI123093
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

agent-based modelingcells-T cellscytotoxicinfections-bacterialpulmonarytransforming growth factor betatuberculosis

Identifiers

PMID29326718
PMCPMC5742530
OpenAlexW2779535723

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.