Evidence map›Paper›PMID 29326609›Full record

ArticleFrontiers in psychiatry2017

A Biomarker to Differentiate between Primary and Cocaine-Induced Major Depression in Cocaine Use Disorder: The Role of Platelet IRAS/Nischarin (I

Benjamin Keller, Joan-Ignasi Mestre-Pinto, María Álvaro-Bartolomé, Diana Martinez-Sanvisens, Magí Farre, M Julia García-Fuster, Jesús A García-Sevilla, Marta Torrens, NEURODEP Group

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Review
  3. The Tryptophan System in Cocaine-Induced Depression.Journal of clinical medicine · 2020
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 1 country.

Benjamin KellerLaboratori de Neurofarmacologia, IUNICS, Universitat de les Illes Balears (UIB), Fundació Institut d'Investigació Sanitària Illes Balears (IdISBa), Palma, Majorca, Spain.
Joan-Ignasi Mestre-PintoRedes Temáticas de Investigación Cooperativa en Salud - Red de Trastornos Adictivos (RETICS-RTA), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
María Álvaro-BartoloméLaboratori de Neurofarmacologia, IUNICS, Universitat de les Illes Balears (UIB), Fundació Institut d'Investigació Sanitària Illes Balears (IdISBa), Palma, Majorca, Spain.
Diana Martinez-SanvisensRedes Temáticas de Investigación Cooperativa en Salud - Red de Trastornos Adictivos (RETICS-RTA), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
Magí FarreRedes Temáticas de Investigación Cooperativa en Salud - Red de Trastornos Adictivos (RETICS-RTA), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
M Julia García-FusterLaboratori de Neurofarmacologia, IUNICS, Universitat de les Illes Balears (UIB), Fundació Institut d'Investigació Sanitària Illes Balears (IdISBa), Palma, Majorca, Spain.
Jesús A García-SevillaLaboratori de Neurofarmacologia, IUNICS, Universitat de les Illes Balears (UIB), Fundació Institut d'Investigació Sanitària Illes Balears (IdISBa), Palma, Majorca, Spain.
Marta TorrensRedes Temáticas de Investigación Cooperativa en Salud - Red de Trastornos Adictivos (RETICS-RTA), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.
NEURODEP Group
Hospital del Mar Research Institute · ESUniversitat de les Illes Balears · ESHealth Research Institute of the Balearic Islands · ESInstituto de Salud Carlos III · ESResearch Institute of Health Sciences · ESUniversitat Autònoma de Barcelona · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The association of cocaine use disorder (CUD) and comorbid major depressive disorder (MDD; CUD/MDD) is characterized by high prevalence and poor treatment outcomes. CUD/MDD may be primary (primary MDD) or cocaine-induced (CUD-induced MDD). Specific biomarkers are needed to improve diagnoses and therapeutic approaches in this dual pathology. Platelet biomarkers [5-HT

Indexed as

acute tryptophan depletionantidepressant drugscocaine-induced depressioncocaine use disorderIRAS/nischarinmajor depressive disorderplatelet biomarker

Identifiers

PMID29326609
PMCPMC5757145
OpenAlexW2790850393

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.