ArticleFrontiers in neuroscience2017
Coordinated Morphogenetic Mechanisms Shape the Vertebrate Eye.
Article in Frontiers in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Identification of 4 novel human ocular coloboma genes ANK3, BMPR1B, PDGFRA, and CDH4 through evolutionary conserved vertebrate gene analysis.Genetics in medicine : official journal of the American College of Medical Genetics · 2022Pooled it
- Genetic mechanism regulating diversity in the placement of eyes on the head of animals.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Notch pathway mutants do not equivalently perturb mouse embryonic retinal development.PLoS genetics · 2023Article
- Optic cup morphogenesis across species and related inborn human eye defects.Development (Cambridge, England) · 2023Review
- Cell fate decisions, transcription factors and signaling during early retinal development.Progress in retinal and eye research · 2022Review
- Shutdown corner, a large deletion mutant isolated from a haploid mutagenesis screen in zebrafish.G3 (Bethesda, Md.) · 2022Article
- Article
- Stretching of the retinal pigment epithelium contributes to zebrafish optic cup morphogenesis.eLife · 2021Article
- Build me up optic cup: Intrinsic and extrinsic mechanisms of vertebrate eye morphogenesis.Developmental biology · 2021Review
- Article
- Analysis of gene network bifurcation during optic cup morphogenesis in zebrafish.Nature communications · 2021Article
- Multiple roles for Pax2 in the embryonic mouse eye.Developmental biology · 2021Article
- Nf2 fine-tunes proliferation and tissue alignment during closure of the optic fissure in the embryonic mouse eye.Human molecular genetics · 2020Article
- A 3D Brillouin microscopy dataset of theData in brief · 2020Article
- An energy landscape approach to understanding variety and robustness in tissue morphogenesis.Biomechanics and modeling in mechanobiology · 2020Article
- The hedgehog pathway and ocular developmental anomalies.Human genetics · 2019Review
- Looking to the future of zebrafish as a model to understand the genetic basis of eye disease.Human genetics · 2019Review
- Article
- The peripheral eye: A neurogenic area with potential to treat retinal pathologies?Progress in retinal and eye research · 2019Review
- Setting Eyes on the Retinal Pigment Epithelium.Frontiers in cell and developmental biology · 2018Review
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The molecular bases of vertebrate eye formation have been extensively investigated during the past 20 years. This has resulted in the definition of the backbone of the gene regulatory networks controlling the different steps of eye development and has further highlighted a substantial conservation of these networks among vertebrates. Yet, the precise morphogenetic events allowing the formation of the optic cup from a small group of cells within the anterior neural plate are still poorly understood. It is also unclear if the morphogenetic events leading to eyes of very similar shape are indeed comparable among all vertebrates or if there are any species-specific peculiarities. Improved imaging techniques have enabled to follow how the eye forms in living embryos of a few vertebrate models, whereas the development of organoid cultures has provided fascinating tools to recapitulate tissue morphogenesis of other less accessible species. Here, we will discuss what these advances have taught us about eye morphogenesis, underscoring possible similarities and differences among vertebrates. We will also discuss the contribution of cell shape changes to this process and how morphogenetic and patterning mechanisms integrate to assemble the final architecture of the eye.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.