Evidence map›Paper›PMID 29326176›Full record

ArticleMolecular & cellular proteomics : MCP2018

Combinatorial Omics Analysis Reveals Perturbed Lysosomal Homeostasis in Collagen VII-deficient Keratinocytes.

Kerstin Thriene, Björn Andreas Grüning, Olivier Bornert, Anika Erxleben, Juna Leppert, Ioannis Athanasiou, Ekkehard Weber, Dimitra Kiritsi, Alexander Nyström, Thomas Reinheckel and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Molecular & cellular proteomics : MCP, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Diagnostic potential of Type VII Collagen during oral carcinogenesis.Journal of applied oral science : revista FOB · 2023
    Article
  5. Collagen VII maintains proteostasis in dermal fibroblasts by scaffolding TANGO1 cargo.Matrix biology : journal of the International Society for Matrix Biology · 2022
    Article
  6. Bacterial lectin BambL acts as a B cell superantigen.Cellular and molecular life sciences : CMLS · 2021
    Article
  7. Article
  8. Review
  9. Signatures of Dermal Fibroblasts from RDEB Pediatric Patients.International journal of molecular sciences · 2021
    Article
  10. Review
  11. Article
  12. Review
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Kerstin ThrieneFrom the ‡Department of Dermatology, Medical Center - University of Freiburg, Germany.
Björn Andreas Grüning§Centre for Biological Systems Analysis (ZBSA), University of Freiburg, Germany.
Olivier BornertFrom the ‡Department of Dermatology, Medical Center - University of Freiburg, Germany.
Anika Erxleben§Centre for Biological Systems Analysis (ZBSA), University of Freiburg, Germany.
Juna LeppertFrom the ‡Department of Dermatology, Medical Center - University of Freiburg, Germany.
Ioannis AthanasiouFrom the ‡Department of Dermatology, Medical Center - University of Freiburg, Germany.
Ekkehard Weber‖Institute of Physiological Chemistry, Medical Faculty, Martin Luther University Halle-Wittenberg, Germany.
Dimitra KiritsiFrom the ‡Department of Dermatology, Medical Center - University of Freiburg, Germany.
Alexander NyströmFrom the ‡Department of Dermatology, Medical Center - University of Freiburg, Germany.
Thomas Reinheckel**Institute of Molecular Medicine and Cell Research, Faculty of Medicine, University of Freiburg, Germany.
Rolf Backofen§Centre for Biological Systems Analysis (ZBSA), University of Freiburg, Germany.
Cristina HasFrom the ‡Department of Dermatology, Medical Center - University of Freiburg, Germany.
Leena Bruckner-TudermanFrom the ‡Department of Dermatology, Medical Center - University of Freiburg, Germany; joern.dengjel@unifr.ch bruckner-tuderman@uniklinik-freiburg.de.
Jörn DengjelFrom the ‡Department of Dermatology, Medical Center - University of Freiburg, Germany; joern.dengjel@unifr.ch bruckner-tuderman@uniklinik-freiburg.de.
University of Freiburg · DEUniversity Medical Center Freiburg · DEMartin Luther University Halle-Wittenberg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The extracellular matrix protein collagen VII is part of the microenvironment of stratified epithelia and critical in organismal homeostasis. Mutations in the encoding gene

Indexed as

Cells, CulturedCollagen Type VIIHomeostasisHumansKeratinocytesLysosomesMutationProteomeTranscriptomeCOL7A1 protein, humanCollagen Type VIIProteome

Identifiers

PMID29326176
PMCPMC5880109
OpenAlexW2783125175

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.